111223-26-8 Usage
Uses
Antihypertensive.
Check Digit Verification of cas no
The CAS Registry Mumber 111223-26-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,2,2 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 111223-26:
(8*1)+(7*1)+(6*1)+(5*2)+(4*2)+(3*3)+(2*2)+(1*6)=58
58 % 10 = 8
So 111223-26-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H33N2O6P/c22-14-6-4-13-19(20(24)23-15-8-12-18(23)21(25)26)29-30(27,28)16-7-5-11-17-9-2-1-3-10-17/h1-3,9-10,18-19H,4-8,11-16,22H2,(H,25,26)(H,27,28)/t18-,19-/m0/s1
111223-26-8Relevant articles and documents
(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]- -proline, a novel orally active inhibitor of ACE
Karanewsky,Badia,Cushman,DeForrest,Dejneka,Loots,Perri,Petrillo Jr.,Powell
, p. 204 - 212 (2007/10/02)
The synthesis of a series of orally active, phosphinyloxyacyl proline inhibitors of angiotensin converting enzyme (ACE) is described. The in vitro and in vivo ACE inhibitory activities are reported for each compound. The structure-activity relationship fo
