1116-22-9

• 

• Basic information

  1. Product Name: H-GAMMA-GLU-GLU-OH
  2. Synonyms: gamma-glutamylglutamate;L-GLUTAMYL-L-GLUTAMIC ACID;L-GAMMA-GLUTAMYL-L-GLUTAMIC ACID;H-GLU(GLU)-OH;H-GLU(GLU-OH)-OH;H-GAMMA-GLU-GLU-OH;GAMMA-GLU-GLU;GAMMA-L-GLUTAMYL-L-GLUTAMIC ACID
  3. CAS NO:1116-22-9
  4. Molecular Formula: C₁₀H₁₆N₂O₇
  5. Molecular Weight: 276.24
  6. EINECS: 214-233-2
  7. Product Categories: N/A
  8. Mol File: 1116-22-9.mol
  9. Article Data: 9

• Chemical Properties

  1. Melting Point: 179-182 °C
  2. Boiling Point: 419.15°C (rough estimate)
  3. Flash Point: 355.4oC
  4. Appearance: White/Powder
  5. Density: 1.3652 (rough estimate)
  6. Refractive Index: 1.4550 (estimate)
  7. Storage Temp.: -15°C
  8. Solubility: Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly)
  9. PKA: 2.21±0.10(Predicted)
  10. CAS DataBase Reference: H-GAMMA-GLU-GLU-OH(CAS DataBase Reference)
  11. NIST Chemistry Reference: H-GAMMA-GLU-GLU-OH(1116-22-9)
  12. EPA Substance Registry System: H-GAMMA-GLU-GLU-OH(1116-22-9)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: 24/25
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 1116-22-9(Hazardous Substances Data)

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• SDS
• Upstream product
• Downstream Products
• Article

1116-22-9 Suppliers

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  Cas No: 1116-22-9

• USD $ 1.2-5.0 / Kiloliter

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• Pharmaceutical Grade CAS 1116-22-9 with competitive price

  Cas No: 1116-22-9

• USD $ 139.0-210.0 / Kilogram

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  Cas No: 1116-22-9

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• Dayang Chem (Hangzhou) Co.,Ltd.
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• L-Glutamic acid, L-g-glutamyl-

  Cas No: 1116-22-9

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• L-Glutamic acid, L-g-glutamyl-

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• Hangzhou J&H Chemical Co., Ltd.
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• γ-L-Glutamyl-L-glutamicacid

  Cas No: 1116-22-9

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• L-Glutamic acid, L-g-glutamyl-

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1116-22-9 Usage

Chemical Properties

white powder

Definition

ChEBI: A dipeptide obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of another glutamic acid.

Check Digit Verification of cas no

The CAS Registry Mumber 1116-22-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,1 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1116-22:
(6*1)+(5*1)+(4*1)+(3*6)+(2*2)+(1*2)=39
39 % 10 = 9
So 1116-22-9 is a valid CAS Registry Number.

1116-22-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	H-γ-GLU-GLU-OH

1.2 Other means of identification

Product number	-
Other names	gamma-L-Glutamyl-L-glutamic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1116-22-9 SDS

1116-22-9Upstream product

• 6893-26-1 D-Glutamic acid 
• 13515-99-6 D-glutamic acid dimethyl ester hydrochloride 
• 86938-17-2 2-(S)-tert-butoxycarbonylaminopentanedioic acid 1-ethyl ester 
• 7365-91-5 C₃₉H₄₀N₂O₉ 
• 23150-65-4 L-glutamic dimethyl ester hydrochloride 
• 449171-15-7 Boc-D-Glu-OEt 
• 13030-09-6 1-benzyl L-glutamate 
• 2768-50-5 dibenzyl L-glutamate 
• 56-86-0 L-glutamic acid 
• 3705-42-8 Cbz-(L)-Glu-OBn 
• 7365-90-4 benzyloxycarbonyl-α-benzyl-γ-L-glutamyl-D-glutamic acid dibenzyl ester 
• 4124-76-9 N-(benzyloxycarbonyl)-L-glutamic acid anhydride 
• 5672-81-1 (4S)-4-{[(benzyloxy)carbonyl]amino}-5-ethoxy-5-oxopentanoic acid 
• 4510-09-2 N-benzyloxycarbonyl-L-glutamic acid-5-hydrazide 

1116-22-9Downstream Products

• 56-86-0 L-glutamic acid 
• 132487-02-6 (6R)-5,10-dideaza-5,6,7,8-tetrahydropteroyl-L-glutamate-γ-L-glutamate 
• 866557-09-7 (6S)-5,10-dideaza-5,6,7,8-tetrahydropteroyl-L-glutamate-γ-L-glutamate 

1116-22-9Relevant articles and documents

γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of the ionotropic glutamate receptor binding pocket

Tamborini, Lucia,Nicosia, Veronica,Conti, Paola,Dall'Oglio, Federica,De Micheli, Carlo,Nielsen, Birgitte,Jensen, Anders A.,Pickering, Darryl S.,Pinto, Andrea

, p. 8486 - 8492 (2016/11/28)

γ-Glutamyl-dipeptides, built by condensing the distal carboxylate of L-Glu (or D-Glu) onto a series of differently functionalized amino acids, were prepared and used as tools for rapidly probing the stereo-electronic properties of iGluRs, searching for subtype-selective ligands.

Microstructure of poly(γ-glutamic acid) produced by Bacillus subtilis consisting of clusters of D- and L-glutamic acid repeating units

Wang, Fei,Ishiguro, Masaji,Mutsukado, Mai,Fujita, Ken-Ichi,Tanaka, Toshio

experimental part, p. 4225 - 4228 (2010/03/31)

Poly(γ-glutamic acid) (PGA) produced by a strain of Bacillus subtilis was partially hydrolyzed into various oligopeptides so that the dipeptide fraction was isolated by the preparative thin-layer chromatography. HPLC analysis was applied to the detection of each of the four stereoisomers in this fraction using chemically synthesized authentic samples. The fraction consisted of N-γ-D-glutamyl-D-glutamic acid, N-γ-L-glutamyl-L-glutamic acid, N-γ-D-glutamyl-L-glutamic acid, and N-γ-L-glutamyl-D-glutamic acid at a ratio of 5.9:6.0:1.0:1.0. On the basis of this result, a model was proposed for the microstructure of the bacterial PGA, in which D- and L-glutamic acid repeating units are alternately linked in a single chain of the molecule.

Effective formation of di- and tri-gamma-glutamates by gamma-glutamyltranspeptidase.

Watanabe,Kohashi

, p. 115 - 116 (2007/10/02)

Using gamma-glutamyltranspeptidase, conditions for di- and tri-gamma-glutamates synthesis were studied with glutamine and glutamic acid esters as substrates. The reactivity of amino acid esters was higher than for free ones. The efficient conditions were the combination of glutamine ethyl and glutamate diethyl esters with a molar ratio of 1/10 at pH 7-8.

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