112457-95-1 Usage
Description
SM 3997 is a compound with various applications across different industries, particularly in pharmaceuticals and drug delivery systems. It is known for its potent activity and selectivity towards specific receptors, making it a valuable asset in the development of anxiolytic and antidepressant medications.
Uses
Used in Pharmaceutical Industry:
SM 3997 is used as an anxiolytic agent for the treatment of anxiety disorders. Its high potency and selectivity for the 5-HT1A receptor (with a Ki value of 27 nM) make it an effective anti-anxiety agent, providing relief for patients suffering from anxiety-related conditions.
Furthermore, SM 3997 is used as an antidepressant, contributing to the treatment of depression by targeting and modulating specific receptors in the brain. Its lower potency at other receptors, such as 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM), ensures a focused therapeutic effect with minimal side effects.
Used in Drug Delivery Systems:
In order to enhance the efficacy and bioavailability of SM 3997, various drug delivery systems have been developed. These systems employ organic and metallic nanoparticles as carriers for the compound, aiming to improve its delivery and therapeutic outcomes. By utilizing these advanced drug delivery methods, the overall effectiveness of SM 3997 in treating anxiety and depression can be significantly improved, leading to better patient outcomes and quality of life.
Check Digit Verification of cas no
The CAS Registry Mumber 112457-95-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,4,5 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 112457-95:
(8*1)+(7*1)+(6*2)+(5*4)+(4*5)+(3*7)+(2*9)+(1*5)=111
111 % 10 = 1
So 112457-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C21H29N5O2.C6H8O7/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21;7-3(8)1-6(13,5(11)12)2-4(9)10/h3,6-7,15-18H,1-2,4-5,8-14H2;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t15-,16-,17-,18+;/m1./s1
112457-95-1Relevant articles and documents
A 5-hydroxytryptamine receptor agonist, a preparing method thereof and uses of the receptor agonist
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Paragraph 0073; 0074, (2017/03/14)
A novel crystal of (3a[alpha],4[beta],7[beta],7a[alpha])-hexahydro-2-[4[4-(2-pyrimidinyl)-1-(piperazinyl)]-butyl]-4,7-methylene-1H-isoindole-1,3(2H)-dione citrate monohydrate, a preparing method thereof and uses of the crystal are disclosed. The molecular formula of the (3a[alpha],4[beta],7[beta],7a[alpha])-hexahydro-2-[4[4-(2-pyrimidinyl)-1-(piperazinyl)]-butyl]-4,7-methylene-1H-isoindole-1,3(2H)-dione citrate monohydrate is CHN5O.C6H8O.H2O. The novel crystal increases stability and solubility of products at present, thus facilitating product preparation and application and increasing medicine safety and effectiveness.
