112888-76-3 Usage
General Description
Tert-Butyl 4-(2-propynylamino)benzoate is a chemical compound consisting of a tert-butyl group, a benzene ring, and an amino group with a propynyl substituent. It is commonly used as a building block in organic synthesis, particularly for the production of pharmaceuticals and agrochemicals. The tert-butyl group provides steric hindrance, which can help improve the compound's stability and solubility in nonpolar solvents, while the propynylamino moiety can participate in various chemical reactions, making it a versatile intermediate in organic chemistry. It may also have potential applications in the development of new materials or as a precursor for the synthesis of biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 112888-76-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,8,8 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 112888-76:
(8*1)+(7*1)+(6*2)+(5*8)+(4*8)+(3*8)+(2*7)+(1*6)=143
143 % 10 = 3
So 112888-76-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H17NO2/c1-5-10-15-12-8-6-11(7-9-12)13(16)17-14(2,3)4/h1,6-9,15H,10H2,2-4H3
112888-76-3Relevant articles and documents
SYNTHESIS OF CYCLOPENTAQUINAZOLINES
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Page/Page column 61-62, (2012/02/05)
A method of producing 6-amino-cyclopenta[g]quinazolines, in enantiomerically enriched form, is provided. In particular, the method may be applicable to the synthesis of N-{N-{4- [N-((6S)-2-hydroxymethyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclo-penta[g]quinazolin
Quinazoline antifolate thymidylate synthase inhibitors: Replacement of glutamic acid in the C2-methyl series
Marsham,Jackman,Barker,Boyle,Pegg,Wardleworth,Kimbell,O'Connor,Calvert,Hughes
, p. 994 - 1004 (2007/10/02)
The synthesis of a series of analogues of the potent thymidylate synthase (TS) inhibitor N-[4[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N- prop-2-ynylamino]benzoyl]-L-glutamic acid (ICI 198583, 1) is described in which the glutamic acid residu
