113102-01-5Relevant articles and documents
Synthesis of tokaramide A, a cysteine protease inhibitor from marine sponge Theonella aff. mirabilis
Konno, Hiroyuki,Nosaka, Kazuto,Akaji, Kenichi
experimental part, p. 9067 - 9071 (2011/12/01)
The first synthesis of tokaramide A (1) is described. Tokaramide A (1) was synthesized via the peptide with a side-chain unprotected arginine residue on Weinreb AM resin by reductive cleavage.
4-ALKOXY-N- (2-HYDROXYCARBAMOYL-2-PIPERIDINYL-ETHYL) -BENZAMIDE COMPOUNDS AS SELECTIVE TACE-INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES
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, (2011/04/19)
The present invention relates to novel benzene- carboxamide compounds having a structure that corresponds to the general formula (I) below: and also to their method of synthesis and to their use in pharmaceutical compositions intended for use in human or