113145-70-3 Usage
Uses
(R)-(-)-Niguldipine Hydrochloride is a potent chemosensitizer in multidrug resistant cells.
Biological Activity
L-type Ca 2+ channel blocker and α 1A -adrenoceptor antagonist; less active enantiomer.
Biochem/physiol Actions
Less active enantiomer
Check Digit Verification of cas no
The CAS Registry Mumber 113145-70-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,1,4 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 113145-70:
(8*1)+(7*1)+(6*3)+(5*1)+(4*4)+(3*5)+(2*7)+(1*0)=83
83 % 10 = 3
So 113145-70-3 is a valid CAS Registry Number.
InChI:InChI=1/C36H39N3O6.ClH/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29;/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3;1H/t33-;/m1./s1
113145-70-3Relevant articles and documents
Optically-active 1,4-dihydropyridine
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, (2008/06/13)
The invention relates to 3-methyl-5-[3-(4,4-diphenylpiperid-1-yl)-propyl] (+)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-piperidine-3,5-dicarboxylate and its salts and to their preparation and use.