115453-82-2 Usage
Uses
Different sources of media describe the Uses of 115453-82-2 differently. You can refer to the following data:
1. Substrate for monitoring the activity of cytochrome P450 in diverse cells and research issues, including in vitro cytotxity testing, regulation and drug metabolization.
2. 7-Ethoxy-4-(trifluoromethyl)coumarin is a fluorogenic substrate used for determining cytochrome P450 activity.
Check Digit Verification of cas no
The CAS Registry Mumber 115453-82-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,4,5 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 115453-82:
(8*1)+(7*1)+(6*5)+(5*4)+(4*5)+(3*3)+(2*8)+(1*2)=112
112 % 10 = 2
So 115453-82-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H9F3O3/c1-2-17-7-3-4-8-9(12(13,14)15)6-11(16)18-10(8)5-7/h3-6H,2H2,1H3
115453-82-2Relevant articles and documents
Synthesis of 7-alkoxy-4-trifluoromethylcoumarins via the von Pechmann reaction catalyzed by molecular iodine
Degrote, Jami,Tyndall, Stephen,Wong, Koon Fai,Vanalstine-Parris, Melissa
, p. 6715 - 6717 (2014)
The synthesis of a series of 7-alkoxy-4-trifluoromethylcoumarins via the von Pechmann reaction catalyzed by molecular iodine is described. The reaction protocol is simple, inexpensive and leads to the formation of the corresponding coumarin derivatives in good yield and high purity. A key intermediate as well as several iodo byproducts were isolated.
