117528-59-3Relevant articles and documents
A novel approach to Finafloxacin hydrochloride (BAY35-3377)
Hong, Jian,Zhang, Zonghua,Lei, Huoxing,Cheng, Haiying,Hu, Yufang,Yang, Wanliang,Liang, Yinglin,Das, Debasis,Chen, Shu-Hui,Li, Ge
experimental part, p. 2525 - 2528 (2009/09/06)
Finafloxacin hydrochloride, an important clinical compound was synthesized by a novel synthetic approach. An active intermediate ethyl 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 19 was prepared by a new route. The chiral (S,S′)-N-Boc 10 was derived from protected pyrrolidine and the absolute stereochemistry was established by X-ray analysis.
3-cyano-2,4,5-trifluoro-benzoyl fluoride and intermediate products for the production thereof
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, (2008/06/13)
The present invention relates to 3-cyano-2,4,5-trifluorobenzoyl fluoride and to intermediates for its preparation and to the process for the preparation of 3-cyano-2,4,5-trifluoro-benzoyl fluoride, which starts from 5 fluoro-1,3-xylene (VIII); which is bi