119285-07-3 Usage
General Description
4-(5-Aminopyridin-2-yl)piperazine-1-carboxylic Acid Tert-butyl Ester is a chemical compound that is typically utilized in the field of medicinal chemistry and pharmaceuticals. It belongs to a larger group of complex substances often employed in drug discovery and development processes due to their bioactive properties. This specific compound is characterized by its molecular inclusion of a pyridinyl group, an aminopyridine moiety, a piperazine ring, and a carboxylic acid ester structure. Its participation in various interactions within biological processes provides a foundation for potential therapeutic applications. The precise biochemical effects, toxicology information, and other specifics regarding this compound are subject to scientific research and may vary depending on the context of use.
Check Digit Verification of cas no
The CAS Registry Mumber 119285-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,2,8 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 119285-07:
(8*1)+(7*1)+(6*9)+(5*2)+(4*8)+(3*5)+(2*0)+(1*7)=133
133 % 10 = 3
So 119285-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)12-5-4-11(15)10-16-12/h4-5,10H,6-9,15H2,1-3H3
119285-07-3Relevant articles and documents
Identification of 2-aminooxazole amides as acyl-CoA: Diacylglycerol acyltransferase 1 (DGAT1) inhibitors through scaffold hopping strategy
Kim, Hyunjin M.,Smith, Michelle D.,Kim, Jae-Hun,Caplen, Mary Ann,Chan, Tin Yau,McKittrick, Brian A.,Cook, John A.,Van Heek, Margaret,Lachowicz, Jean
, p. 6410 - 6414 (2013)
A scaffold hopping strategy was successfully applied in discovering 2-aminooxazole amides as potent DGAT1 inhibitors for the treatment of dyslipidemia. Further optimization in potency and PK properties resulted in a lead series with oral in vivo efficacy in a mouse postprandial triglyceridemia (PPTG) assay.
SMALL MOLECULE INHIBITORS OF GALECTIN-3
-
, (2021/11/20)
The present disclosure relates to compounds of Formula (I), which inhibit Gal-3, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods using and making such compounds and compositions. (Formula (I))
HETEROCYCLIC COMPOUNDS AND USES THEREOF
-
, (2019/04/25)
Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.