119630-94-3 Usage
Biological Activity
Mixed opioid receptor agonist/antagonist. Acts as a potent and full agonist at κ , and a partial agonist at μ and δ opioid receptors (pEC 50 values are 9.45, 8.74 and 8.61 in a cAMP assay, 9.70, 8.59 and 8.49 in a [ 35 S]GTP γ S binding assay respectively). Fails to exert agonist effects at NOP receptors and antagonizes agonist-induced NOP activation. Stimulates κ -, μ - and δ -mediated analgesia and blocks NOP-induced supraspinal nociception.
Check Digit Verification of cas no
The CAS Registry Mumber 119630-94-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,6,3 and 0 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 119630-94:
(8*1)+(7*1)+(6*9)+(5*6)+(4*3)+(3*0)+(2*9)+(1*4)=133
133 % 10 = 3
So 119630-94-3 is a valid CAS Registry Number.
InChI:InChI=1/C26H27N3O4/c1-2-13-29-14-12-25-21-17-8-9-19(30)22(21)33-23(25)18(10-11-26(25,32)20(29)15-17)27-28-24(31)16-6-4-3-5-7-16/h2-9,20,23,30,32H,1,10-15H2,(H,28,31)/b27-18+/t20-,23-,25?,26?/m1/s1
