1197-78-0Relevant articles and documents
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Kuwajima,Nakamura
, p. 3257 (1975)
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Thioalkylation of Enolates, II. α-Thioalkylation of Zinc Enolates to α,α-Disubstituted Ketones
Groth, Ulrich,Huhn, Thomas,Richter, Norbert
, p. 49 - 54 (2007/10/02)
An α-alkylation of the 2-methylcycloalkanones 1 and 4 at the higher substituted carbon can be achieved by thioalkylation of the corresponding zinc enolates with the α-chlorosulfides 3.The desulfurization can be carried out with either Raney nickel or lithium in diethylamine for compounds which contain double or triple bonds. Key Words: Zinc enolates, thioalkylation of / Ketones, α,α-disubstituted / Desulfurization
Absolute Configuration of 1,2-Disubstituted trans-Cyclodecenes Based on Chemical Correlation with (+)-Dimethyl (2R)-2-Butyl-1-methyloctanedioate
Marshall, James A.,Flynn, Katherine E.
, p. 7430 - 7435 (2007/10/02)
The absolute configuration of (-)-trans-1,2-dimethylcyclodecene (4) has been determined to be R through chemical correlation with (+)-dimethyl (2R)-2-butyl-2-methyloctanedioate (13).Diester 13 was prepared from (+)-(4aS)-4a-methyl-2,3,4,4a,5,6,7,8-octahyd