1201-08-7 Usage
General Description
8-BROMO-4-HYDROXY-2-METHYLQUINOLINE is a chemical compound with the formula C10H8BrNO. It is a derivative of quinoline, a heterocyclic aromatic compound. This chemical contains a bromine atom and a hydroxyl group, as well as a methyl group attached to the quinoline ring. It may be used in pharmaceutical research and drug development as a building block for synthesizing other compounds. It also has potential applications in the field of materials science, particularly in the development of photoactive materials and dyes. Its specific properties and potential uses may be further explored through research and experimentation.
Check Digit Verification of cas no
The CAS Registry Mumber 1201-08-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,0 and 1 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1201-08:
(6*1)+(5*2)+(4*0)+(3*1)+(2*0)+(1*8)=27
27 % 10 = 7
So 1201-08-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H8BrNO/c1-6-5-9(13)7-3-2-4-8(11)10(7)12-6/h2-5H,1H3,(H,12,13)
1201-08-7Relevant articles and documents
Highly Enantioselective Iron-Catalyzed cis-Dihydroxylation of Alkenes with Hydrogen Peroxide Oxidant via an FeIII-OOH Reactive Intermediate
Zang, Chao,Liu, Yungen,Xu, Zhen-Jiang,Tse, Chun-Wai,Guan, Xiangguo,Wei, Jinhu,Huang, Jie-Sheng,Che, Chi-Ming
supporting information, p. 10253 - 10257 (2016/08/24)
The development of environmentally benign catalysts for highly enantioselective asymmetric cis-dihydroxylation (AD) of alkenes with broad substrate scope remains a challenge. By employing [FeII(L)(OTf)2] (L=N,N′-dimethyl-N,N′-bis(2-methyl-8-quinolyl)-cyclohexane-1,2-diamine) as a catalyst, cis-diols in up to 99.8 % ee with 85 % isolated yield have been achieved in AD of alkenes with H2O2as an oxidant and alkenes in a limiting amount. This “[FeII(L)(OTf)2]+H2O2” method is applicable to both (E)-alkenes and terminal alkenes (24 examples >80 % ee, up to 1 g scale). Mechanistic studies, including18O-labeling, UV/Vis, EPR, ESI-MS analyses, and DFT calculations lend evidence for the involvement of chiral FeIII-OOH active species in enantioselective formation of the two C?O bonds.