121014-53-7 Usage
General Description
BIG ET-1 (1-38) (HUMAN) is a peptide hormone that belongs to the endothelin protein family. It is a precursor molecule of endothelin-1, a vasoconstrictive peptide that plays a significant role in the regulation of blood pressure and vascular tone. The "BIG" in its name stands for "big endothelin" and refers to the larger molecular size of the peptide before it is processed into the biologically active form. This precursor form is cleaved to produce endothelin-1, which binds to endothelin receptors in the vascular smooth muscle cells, leading to vasoconstriction. The peptide is produced in various tissues, including the endothelium, and plays a role in physiological processes such as the regulation of blood flow and maintaining cardiovascular homeostasis. Dysregulation of endothelin-1 has been implicated in various cardiovascular diseases, making it an important target for therapeutic interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 121014-53-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,0,1 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 121014-53:
(8*1)+(7*2)+(6*1)+(5*0)+(4*1)+(3*4)+(2*5)+(1*3)=57
57 % 10 = 7
So 121014-53-7 is a valid CAS Registry Number.