1212-48-2 Usage
General Description
2-benzyl-1H-benzimidazole monohydrochloride is a chemical compound that is often used in pharmaceutical research and development. It is a hydrochloride salt of 2-benzyl-1H-benzimidazole, a benzimidazole derivative with potential anti-tumor and anti-cancer properties. 2-benzyl-1H-benzimidazole monohydrochloride has been studied for its potential effects on inhibiting the growth of cancer cells and suppressing tumor growth. It is also being investigated for its potential use in the treatment of gastrointestinal cancer and other types of solid tumors. The hydrochloride salt form of this compound makes it more stable and soluble, which may be beneficial for formulation in pharmaceutical applications. Overall, 2-benzyl-1H-benzimidazole monohydrochloride shows promise as a potential anti-cancer agent and is the subject of ongoing research in the field of oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 1212-48-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,1 and 2 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1212-48:
(6*1)+(5*2)+(4*1)+(3*2)+(2*4)+(1*8)=42
42 % 10 = 2
So 1212-48-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H12N2.ClH/c1-2-6-11(7-3-1)10-14-15-12-8-4-5-9-13(12)16-14;/h1-9H,10H2,(H,15,16);1H
1212-48-2Relevant articles and documents
Synthesis method of dibazolum
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Paragraph 0024; 0025; 0026; 0027, (2017/01/17)
The invention provides a synthesis method of dibazolum. The synthesis method comprises the following steps: adding o-phenylenediamine and toluene into a reaction container; dropwise adding phenylacetyl chloride into the reaction container; after dripping, heating and reflowing to react until the reaction is finished; carrying out post-treatment to obtain a dibazolum product. Compared with the prior art, the synthesis method has the following beneficial technical effects that (1) the reaction temperature is reduced so that a reaction for synthesizing the dibazolum can be carried out under a moderate condition; (2) any hydration agent or any catalyst is not added in the synthesis method and side reactions are few, so that impurities are effectively reduced and the number of times of subsequent de-coloring and crystallization is reduced; (3) post-treatment operation is simplified by the synthesis method so that the production cost is saved and large-scale and industrial production is facilitated.