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121712-03-6

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121712-03-6 Usage

Derivatives

Benzimidazole and thioamide

Functional Group

Fluorine atom attached

Application

Pharmaceutical research
Drug development

Specific Uses

Study of antiviral agents
Study of antibacterial agents
Investigation for anti-cancer properties

Research Focus

Mechanisms of action
Therapeutic applications

Check Digit Verification of cas no

The CAS Registry Mumber 121712-03-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,7,1 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 121712-03:
(8*1)+(7*2)+(6*1)+(5*7)+(4*1)+(3*2)+(2*0)+(1*3)=76
76 % 10 = 6
So 121712-03-6 is a valid CAS Registry Number.

121712-03-6Relevant articles and documents

HETEROCYCLIC SYSTEMS CONTAINING BRIDGEHEAD NITROGEN ATOM: PART LXVI. STUDIES OF ORIENTATION OF CYCLIZATION IN THE SYNTHESIS OF 8-FLUOROTHIAZOLOBENZIMIDAZOL-3(2H)-ONE

Dahiya, Rajinder,Pujari, H. K.

, p. 245 - 256 (1989)

2-Fluoro-6-nitroaniline, obtained by nitration of 2-fluoroacetanilide, on reduction with Raney nickel and hydrazine hydrate followed by treatment of the resulting diamine with carbon disulphide in situ gives 4-fluorobenzimidazolyl-2-thione.This thione on condensation with chloroacetic acid gives 4-fluorobenzimidazol-2-thiolacetic acid which on cyclization with a mixture of acetic anhydride and pyridine furnished 8-fluorothiazolobenzimidazol-3(2H)-one as revealed by 1H-NMR spectroscopy.The condensation of 4-fluorobenzimidazolyl-2-thione with 1,2-dibromoethane yields 2,3-dihydro-8-fluorothiazolobenzimidazole and sym-bis-(4-fluorobenzimidazol-2-ylmercapto)ethane.

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