121743-23-5Relevant articles and documents
SYNTHESIS OF SUBSTITUTED TETRAHYDROPYRIDINES AND M-HYDROXYBENZOIC ACIDS
Clinch, K.,Marquez, C. J.,Parrott, M. J.,Ramage, R.
, p. 239 - 258 (2007/10/02)
A series of substituted 1,2,3,6- (5) and 1,2,5,6-tetrahydropyridines (6) have been synthesised via intramolecular 1,6-Michael addition of methoxycarbonyl-2,4-dienylamines (10).The kinetics of these reactions have been investigated and an explanation of substituent effects is advanced.Also a new route to m-hydroxybenzoic acids has been established by cyclisation of substituted hexa-3,4:5,6-dienoic acids.