122665-73-0 Usage
General Description
CMDA, or 1-(2-chloroethyl)piperidinium-2- carboxylate, is a chemical compound that is commonly used in organic synthesis and pharmaceutical research. It is known for its role as an alkylating agent, which means it can add an alkyl group to a molecule by replacing a hydrogen atom. This property makes it useful in the synthesis of many different types of organic compounds, including pharmaceutical drugs. CMDA is also used in the production of certain anti-cancer drugs, where its alkylating properties help to disrupt the DNA of cancer cells, leading to their destruction. Additionally, CMDA is being studied for its potential use in the treatment of diseases such as Parkinson's and Alzheimer's, where its alkylating properties may have therapeutic benefits. Overall, CMDA is a versatile and important chemical in the fields of organic chemistry and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 122665-73-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,6,6 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 122665-73:
(8*1)+(7*2)+(6*2)+(5*6)+(4*6)+(3*5)+(2*7)+(1*3)=120
120 % 10 = 0
So 122665-73-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H23ClN2O8S/c1-29(26,27)28-11-10-20(9-8-18)13-4-2-12(3-5-13)16(23)19-14(17(24)25)6-7-15(21)22/h2-5,14H,6-11H2,1H3,(H,19,23)(H,21,22)(H,24,25)/t14-/m0/s1
122665-73-0Relevant articles and documents
4-amino-fluorobenzamides and their use as cytotoxic prodrugs
-
, (2008/06/13)
The invention provides a compound which is a 3-fluorobenzamide of the formula (A) STR1 wherein R-NH is the residue of an α-amino acid R-NH2 or oligopeptide R-NH2, and M is a nitrogen mustard group of the formula STR2 wherein Y and L, which may be the same or different in a molecule, are leaving groups; or a pharmaceutically acceptable salt thereof. The compounds are useful as prodrugs for treating cancer.
SYNTHESIS OF AN N-MUSTARD PRODRUG
Mann, John,Haase-Held, Margret,Springer, Caroline J.,Bagshawe, Kenneth D.
, p. 5377 - 5382 (2007/10/02)
We describe the synthesis of the novel N-mustard prodrug 4-benzoyl-L-glutamic acid, which is designed for activation by tumour localising antibody-carboxypeptidase conjugates.
