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1230-27-9

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1230-27-9 Usage

General Description

P-NITROPHENYL 1-THIO-BETA-D-GALACTOPYRANOSIDE is a chemical compound that is often used in biochemical research as a substrate for detecting the presence of beta-galactosidase activity. It is a chromogenic substrate that turns yellow when cleaved by beta-galactosidase, making it useful for the detection and quantification of this enzyme in biological samples. P-NITROPHENYL 1-THIO-BETA-D-GALACTOPYRANOSIDE is commonly used in assays to study gene expression, protein function, and cell viability. It is also used in the development of diagnostic tests for various diseases and conditions, as well as in the pharmaceutical industry for drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 1230-27-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,3 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1230-27:
(6*1)+(5*2)+(4*3)+(3*0)+(2*2)+(1*7)=39
39 % 10 = 9
So 1230-27-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO7S/c14-5-8-9(15)10(16)11(17)12(20-8)21-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8?,9-,10+,11-,12+/m1/s1

1230-27-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Nitrophenyl 1-thio-β-D-galactopyranoside

1.2 Other means of identification

Product number -
Other names P-NITROPHENYL 1-THIO-β-D-GALACTOPYRANOSIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1230-27-9 SDS

1230-27-9Relevant articles and documents

Synthesis, biological evaluation, wac and NMR studies of s-galactosides and non-carbohydrate ligands of cholera toxin based on polyhydroxyalkylfuroate moieties

Ramos-Soriano, Javier,Niss, Ulf,Angulo, Jesus,Angulo, Manuel,Moreno-Vargas, Antonio J.,Carmona, Ana T.,Ohlson, Sten,Robina, Inmaculada

, p. 17989 - 18003 (2014/01/17)

The synthesis of several non-carbohydrate ligands of cholera toxin based on polyhydroxyalkylfuroate moieties is reported. Some of them have been linked to D-galactose through a stable and well-tolerated S-glycosidic bond. They represent a novel type of non-hydrolyzable bidentate ligand featuring galactose and polyhydroxyalkylfuroic esters as pharmacophoric residues, thus mimicking the GM1 ganglioside. The affinity of the new compounds towards cholera toxin was measured by weak affinity chromatography (WAC). The interaction of the best candidates with this toxin was also studied by saturation transfer difference NMR experiments, which allowed identification of the binding epitopes of the ligands interacting with the protein. Interestingly, the highest affinity was shown by non-carbohydrate mimics based on a polyhydroxyalkylfuroic ester structure. No carbs here: Saturation transfer difference (STD) NMR studies of bidentate ligands of cholera toxin (see figure, WAC = weak affinity chromatography) show the methylfuran moiety as the main contact point in the interaction with the toxin. Several polyhydroxyalkylfuroate-based structures are synthesized and analyzed and show similar or even better affinity than the bidentate ligands. They constitute the first examples of non-carbohydrate ligands for cholera toxin. Copyright

Mild stereoselective syntheses of thioglycosides under PTC conditions and their use as active and latent glycosyl donors

Cao,Meunier,Andersson,Letellier,Roy

, p. 2303 - 2312 (2007/10/02)

Mild and stereoselective arylthio glycoside syntheses were accomplished by inversion of configuration of glycosyl halides under phase transfer catalyzed conditions. Under such conditions, aryl α-thiosialosides having electron donating and withdrawing subs

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