123016-21-7 Usage
General Description
[S,(+)]-α-Methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid, also known as 6-MNA, is a chemical compound with anti-inflammatory and analgesic properties. It is a derivative of naphthaleneacetic acid and has been shown to have potent activity in animal models of pain and inflammation. 6-MNA acts as a nonsteroidal anti-inflammatory drug (NSAID) and is believed to inhibit the synthesis of prostaglandins, which are chemical messengers involved in the body's inflammatory response. It has been studied as a potential candidate for the treatment of conditions such as rheumatoid arthritis and osteoarthritis. Additionally, 6-MNA has been found to have antioxidant and neuroprotective effects, making it a promising compound for further research and development in the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 123016-21-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,0,1 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 123016-21:
(8*1)+(7*2)+(6*3)+(5*0)+(4*1)+(3*6)+(2*2)+(1*1)=67
67 % 10 = 7
So 123016-21-7 is a valid CAS Registry Number.
InChI:InChI=1/C23H19NO3/c1-15(23(25)26)17-6-7-19-13-21(11-9-18(19)12-17)27-14-20-10-8-16-4-2-3-5-22(16)24-20/h2-13,15H,14H2,1H3,(H,25,26)/t15-/m0/s1
123016-21-7Relevant articles and documents
Quinolinylmethoxy naphthalenepropionic acid derivatives as anti-inflammatory/antiallergic agents
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, (2008/06/13)
There are disclosed compounds of the formula STR1 wherein R is hydrogen or lower alkyl; Y is STR2 or a pharmaceutically acceptable salt thereof, and its use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like, in psoriasis, ulcerative colitis, rheumatoid arthritis as well as in other immediate hypersensitivity reactions.
Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
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, (2008/06/13)
There are disclosed compounds of the formula STR1 wherein A is alkyl of 3-19 carbon atoms, diloweralkyl allyl, dihaloallyl, diphenylallyl, lower alkynyl, STR2 X is N or CR; Z is STR3 R is hydrogen or lower alkyl; R1 is hydrogen, lower alkyl or phenyl; R2 is hydrogen or loweralkyl; or R1 and R2 taken together form a benzene ring; and the pharmaceutically acceptable salts thereof, and their use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like, in psoriasis, ulcerative colitis, rheumatoid arthritis as well as in other immediate hypersensitivity reactions.
