123053-22-5 Usage
Description
L-3-Chlorophenylalanine, a derivative of the amino acid phenylalanine, is a halogenated phenylalanine with a chlorine atom attached to the third carbon of the phenylalanine molecule. It is a potent inhibitor of the enzyme phenylalanine hydroxylase, which plays a crucial role in the metabolism of phenylalanine. L-3-CHLOROPHENYLALANINE has been extensively utilized in scientific research to study the effects of altered phenylalanine metabolism and the role of phenylalanine hydroxylase in various physiological processes. Furthermore, L-3-Chlorophenylalanine has been implicated in the regulation of neurotransmitter levels in the brain, making it a potentially valuable tool for understanding neurological disorders and developing new therapeutic interventions.
Uses
Used in Scientific Research:
L-3-Chlorophenylalanine is used as a research tool for studying the effects of altered phenylalanine metabolism and the role of phenylalanine hydroxylase in various physiological processes. Its ability to inhibit phenylalanine hydroxylase makes it a valuable compound for investigating the consequences of disrupted phenylalanine metabolism on cellular and organismal functions.
Used in Neurological Research:
L-3-Chlorophenylalanine is used as a research compound in the field of neurology to understand its potential role in regulating neurotransmitter levels in the brain. This knowledge can contribute to the development of new therapeutic interventions for neurological disorders associated with neurotransmitter imbalances.
Used in Drug Development:
L-3-Chlorophenylalanine is used as a starting material or a key intermediate in the synthesis of pharmaceutical compounds targeting phenylalanine hydroxylase or neurotransmitter regulation. Its unique properties and inhibitory effects on phenylalanine hydroxylase make it a promising candidate for the development of drugs aimed at treating neurological disorders and other conditions related to phenylalanine metabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 123053-22-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,0,5 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 123053-22:
(8*1)+(7*2)+(6*3)+(5*0)+(4*5)+(3*3)+(2*2)+(1*2)=75
75 % 10 = 5
So 123053-22-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H10ClNO2/c10-7-3-1-2-6(4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1
123053-22-5Relevant articles and documents
synthesis of both enantiomers of chiral phenylalanine derivatives catalyzed by cinchona alkaloid quaternary ammonium salts as asymmetric phase transfer catalysts
Jin, Lei,Zhao, Shuai,Chen, Xin
, (2018)
A practical synthesis of both enantiomers of unnatural phenylalanine derivatives by using two pseudoenantiomeric phase transfer catalysts is described. Through asymmetric α-alkylation of glycine Schiff base with substituted benzyl bromides and 1-(bromomet
