124917-28-8

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• Basic information

  1. Product Name: (7S,9S)-9-acetyl-7-[(2S,5R,6S)-5-amino-6-methyl-oxan-2-yl]oxy-6,9,11-t rihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
  2. Synonyms: (7S,9S)-9-acetyl-7-[(2S,5R,6S)-5-amino-6-methyl-oxan-2-yl]oxy-6,9,11-t rihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
  3. CAS NO:124917-28-8
  4. Molecular Formula: C26H27NO8
  5. Molecular Weight: 481.4945
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 124917-28-8.mol
  9. Article Data: 0

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 681°Cat760mmHg
  3. Flash Point: 365.7°C
  4. Appearance: /
  5. Density: 1.5g/cm³
  6. Vapor Pressure: 1.76E-19mmHg at 25°C
  7. Refractive Index: 1.688
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: (7S,9S)-9-acetyl-7-[(2S,5R,6S)-5-amino-6-methyl-oxan-2-yl]oxy-6,9,11-t rihydroxy-8,10-dihydro-7H-tetracene-5,12-dione(CAS DataBase Reference)
  11. NIST Chemistry Reference: (7S,9S)-9-acetyl-7-[(2S,5R,6S)-5-amino-6-methyl-oxan-2-yl]oxy-6,9,11-t rihydroxy-8,10-dihydro-7H-tetracene-5,12-dione(124917-28-8)
  12. EPA Substance Registry System: (7S,9S)-9-acetyl-7-[(2S,5R,6S)-5-amino-6-methyl-oxan-2-yl]oxy-6,9,11-t rihydroxy-8,10-dihydro-7H-tetracene-5,12-dione(124917-28-8)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 124917-28-8(Hazardous Substances Data)

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• (7S,9S)-9-ACETYL-7-[(2S,5R,6S)-5-AMINO-6-METHYL-OXAN-2-YL]OXY-6,9,11-T RIHYDROXY-8,10-DIHYDRO-7H-TETRACENE-5,12-DIONE

  Cas No: 124917-28-8

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124917-28-8 Usage

General Description

The chemical compound, also known as Doxorubicin, is a type of anthracycline anti-tumor antibiotic isolated from the bacterium Streptomyces peucetius. It is known for its potent antineoplastic properties and is used in the treatment of various types of cancer, including leukemia, lymphoma, and breast cancer. Doxorubicin works by intercalating with DNA and inhibiting the activity of topoisomerase II, preventing DNA replication and ultimately leading to cell death. Additionally, it generates free radicals, leading to oxidative stress and ultimately contributing to its cytotoxic effects. However, its clinical use is limited by its potential cardiotoxicity, which can lead to congestive heart failure, and other adverse effects such as myelosuppression and gastrointestinal toxicity.

Check Digit Verification of cas no

The CAS Registry Mumber 124917-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,9,1 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 124917-28:
(8*1)+(7*2)+(6*4)+(5*9)+(4*1)+(3*7)+(2*2)+(1*8)=128
128 % 10 = 8
So 124917-28-8 is a valid CAS Registry Number.

InChI:InChI=1/C26H27NO8/c1-11-16(27)7-8-18(34-11)35-17-10-26(33,12(2)28)9-15-19(17)25(32)21-20(24(15)31)22(29)13-5-3-4-6-14(13)23(21)30/h3-6,11,16-18,31-33H,7-10,27H2,1-2H3/t11-,16+,17-,18-,26-/m0/s1

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