125310-67-0 Usage
General Description
1-(deoxyguanosin-N(2)-yl)-2-aminophenanthrene is a chemical compound that is formed when the DNA base guanine reacts with 2-aminophenanthrene, a polycyclic aromatic hydrocarbon found in cigarette smoke and other combustion products. 1-(deoxyguanosin-N(2)-yl)-2-aminophenanthrene is a DNA adduct, meaning it forms a covalent bond with the guanine base in DNA. As a result, it can cause mutations in the DNA sequence and potentially lead to cancer. Research has shown that 1-(deoxyguanosin-N(2)-yl)-2-aminophenanthrene is a potent carcinogen and is of particular concern in tobacco smoke-related cancers. Efforts to understand its mechanism of action and develop strategies to prevent its formation are ongoing in the field of cancer research.
Check Digit Verification of cas no
The CAS Registry Mumber 125310-67-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,3,1 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 125310-67:
(8*1)+(7*2)+(6*5)+(5*3)+(4*1)+(3*0)+(2*6)+(1*7)=90
90 % 10 = 0
So 125310-67-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H22N6O4/c25-16-8-7-14-13-4-2-1-3-12(13)5-6-15(14)20(16)27-24-28-22-21(23(33)29-24)26-11-30(22)19-9-17(32)18(10-31)34-19/h1-8,11,17-19,31-32H,9-10,25H2,(H2,27,28,29,33)/t17-,18+,19+/m0/s1