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12584-58-6

12584-58-6

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12584-58-6 Usage

Description

Insulin is a hormone produced by the beta cells of the pancreas, primarily responsible for regulating glucose metabolism in the body. It facilitates the uptake of glucose from the bloodstream into cells, where it can be used for energy or stored for later use. Insulin plays a crucial role in maintaining blood sugar levels within a healthy range and is essential for the proper functioning of various body systems.

Uses

Used in Medical Applications:
Insulin is used as a therapeutic agent for the treatment of diabetes mellitus, a chronic condition characterized by high blood sugar levels due to insufficient insulin production or reduced sensitivity to insulin. It helps manage and control blood sugar levels in both type 1 and type 2 diabetic patients, preventing complications and improving overall health.
Used in Diagnostic Applications:
Insulin is used as a diagnostic tool in various medical tests and procedures, such as the glucose tolerance test, to determine the beta-cell reserve and assess the body's response to glucose intake. It contributes to the diagnosis of insulin and non-insulin-dependent diabetes, as well as the characterization and follow-up of states of glucose intolerance.
Additionally, insulin is used in the diagnosis and study of cases of insulin resistance, a condition where the body's cells do not respond properly to insulin, leading to high blood sugar levels. It is also utilized in the diagnosis of insulinoma, a rare tumor of the pancreas that produces excessive amounts of insulin, causing hypoglycemia (low blood sugar levels).
Chemical Properties:
Insulin is a white or almost white powder with specific chemical properties that allow it to function effectively in the body. Its molecular structure enables it to bind to insulin receptors on cells, initiating a cascade of events that facilitate glucose uptake and utilization.

Biological Functions

Insulin has anabolic properties that include the stimulation of both skeletal muscle and liver cells to incorporate glucose and convert it to glycogen, to synthesize proteins from amino acids in the blood, and to act on fat cells to enhance their uptake of glucose and the synthesis of fat. In short, insulin encourages anabolism rather than catabolism, because it promotes the synthesis of glycogen, proteins, and lipids. A deficiency of insulin, which characterizes the disease diabetes mellitus (DM), causes extreme changes in the entire metabolic pattern of individuals with DM. Patients with DM often demonstrate elevated blood glucose levels, excess glucose in the urine, and failure to properly utilize carbohydrate and lipids.

Check Digit Verification of cas no

The CAS Registry Mumber 12584-58-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,5,8 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 12584-58:
(7*1)+(6*2)+(5*5)+(4*8)+(3*4)+(2*5)+(1*8)=106
106 % 10 = 6
So 12584-58-6 is a valid CAS Registry Number.
InChI:InChI=1/C256H381N65O76S6/c1-29-131(23)205(313-193(337)104-258)251(391)317-204(130(21)22)247(387)288-159(75-82-200(347)348)217(357)282-156(71-78-189(262)333)221(361)308-183-116-401-402-117-184-242(382)305-178(111-323)239(379)294-162(88-123(7)8)224(364)295-168(95-140-53-61-146(327)62-54-140)227(367)283-154(69-76-187(260)331)218(358)290-161(87-122(5)6)222(362)285-158(74-81-199(345)346)220(360)302-174(101-190(263)334)234(374)298-170(97-142-57-65-148(329)66-58-142)230(370)309-182(241(381)304-176(255(396)397)103-192(265)336)115-400-399-114-181(213(353)272-107-194(338)278-153(72-79-197(341)342)216(356)281-151(51-42-84-270-256(266)267)211(351)271-108-195(339)279-166(93-138-46-36-32-37-47-138)226(366)297-167(94-139-48-38-33-39-49-139)229(369)299-171(98-143-59-67-149(330)68-60-143)237(377)320-208(136(28)326)253(393)321-85-43-52-186(321)245(385)286-152(50-40-41-83-257)214(354)277-134(26)254(394)395)311-249(389)203(129(19)20)316-235(375)164(90-125(11)12)292-228(368)169(96-141-55-63-147(328)64-56-141)296-223(363)160(86-12

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