126047-75-4 Usage
Uses
Gly-Pro-Arg-Pro amide has been used-as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombinfor blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from miceduring preparation of human soluble fibrin, to block the polymerization of soluble fibrin
General Description
Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein.
Biochem/physiol Actions
Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).
Check Digit Verification of cas no
The CAS Registry Mumber 126047-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,0,4 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 126047-75:
(8*1)+(7*2)+(6*6)+(5*0)+(4*4)+(3*7)+(2*7)+(1*5)=114
114 % 10 = 4
So 126047-75-4 is a valid CAS Registry Number.