126163-64-2Relevant articles and documents
Preparation method of 2,3-difluorobenzoic acid
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Paragraph 0028; 0030; 0031; 0036, (2018/11/03)
The invention discloses a preparation method of 2,3-difluorobenzoic acid and belongs to the field of organic chemical synthesis. The method comprises the following steps: taking o-difluoro benzene, carrying out substitution reaction to obtain 2,3-difluorobenzene lithium, then carrying out addition reaction to obtain 2,3-difluorobenzoic acid. Through the preparation method of 2,3-difluorobenzoic acid, the production cost is reduced; the pollution to the environment is reduced; the purity and the yield of the product are improved; and the preparation method has the advantages of easily availableraw materials, simplicity and convenience in operation and capability of being suitable for large-scale industrial production.