127682-75-1Relevant articles and documents
SYNTHESYS OF ISO-DDA, MEMBER OF A NOVEL CLASS OF ANTI-HIV AGENTS
Huryn, Donna M.,Sluboski, Barbara C.,Tam, Steve Y,,Todaro, Luis J.,Weigele, Manfred
, p. 6259 - 6262 (1989)
Iso-ddA (3) represents a new class of potential anti-AIDS drugs.Synthetic approaches to this compound involving nucleophilic additions to a novel carbohydrate framework are discussed.
Enantiospecific total synthesis of L-2',3'-dideoxyisonucleosides via regioselective opening of optically active C2-symmetric 1,4-pentadiene bis- epoxide
Jung,Kretschik
, p. 2975 - 2981 (2007/10/03)
A new method for the synthesis of L-2',3'-dideoxyisonucleosides is described. The readily available, optically active C2-symmetric bis-epoxide (2S,4S)-1,2:4,5-diepoxypentane (5) was prepared by a short route from readily available starting mate
Enantiospecific Synthesis of 3'-Hetero-dideoxy Nucleoside Analogues as Potential Anti-HIV Agents
Jones, Martin F.,Noble, Stewart A.,Robertson, Colin A.,Storer, Richard,Highcock, Rona M.,Lamont, R. Brian
, p. 1427 - 1436 (2007/10/02)
Two series of analogues of 2',3'-dideoxy carbocyclic nucleosides, in which the 3'-carbon atom is replaced by either an oxygen or a sulfur atom, have been prepared enantiospecifically from diacetone-L-glucose and diacetone-D-glucose respectively.Within eac