128111-65-9Relevant articles and documents
Novel Process for Preparing Taltirelin and Its Intermediates
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Paragraph 0118-0126, (2020/09/30)
The present invention relates to a novel method for manufacturing taltirelin and an intermediate thereof. More specifically, the present invention discloses: a manufacturing method which uses a fluorenylmethoxycarbonyl (Fmoc)-trityl-histidine as a starting material, and manufactures taltirelin through a process of manufacturing histidyl-trityl-prolineamide, which is an intermediate of talthyreline by an in situ reaction, thereby being suitable for industrial mass production by manufacturing taltirelin in a high yield and high purity in a short time compared to existing technology; and a method for manufacturing histidyl-trityl-prolineamide for the same.