Welcome to LookChem.com Sign In|Join Free

CAS

  • or

129053-84-5

Post Buying Request

129053-84-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

129053-84-5 Usage

General Description

3-[(1H-Pyrrole-2-carbonyl)-amino]propionic acid is a chemical compound with the molecular formula C8H10N2O3. It is an amino acid derivative with a pyrrole-2-carbonyl group attached to the nitrogen atom of the amino acid. 3-[(1H-PYRROLE-2-CARBONYL)-AMINO]PROPIONIC ACID is not naturally occurring but can be synthesized in the laboratory. It is used as a building block for the synthesis of peptides and other bioactive molecules. It may also have potential applications in pharmaceutical research and drug development due to its unique structure and properties. Further research and studies are needed to fully understand the potential uses and effects of 3-[(1H-Pyrrole-2-carbonyl)-amino]propionic acid.

Check Digit Verification of cas no

The CAS Registry Mumber 129053-84-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,0,5 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 129053-84:
(8*1)+(7*2)+(6*9)+(5*0)+(4*5)+(3*3)+(2*8)+(1*4)=125
125 % 10 = 5
So 129053-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O3/c11-7(12)3-5-10-8(13)6-2-1-4-9-6/h1-2,4,9H,3,5H2,(H,10,13)(H,11,12)

129053-84-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(1H-pyrrole-2-carbonylamino)propanoic acid

1.2 Other means of identification

Product number -
Other names 3-<(1H-pyrrole-2-carbonyl)amino>propionic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129053-84-5 SDS

129053-84-5Relevant articles and documents

Synthesis of indolo/pyrroloazepinone-oxindoles as potential cytotoxic, DNA-intercalating and Topo I inhibitors

Bhale, Nagesh A.,George, Joel,Godugu, Chandraiah,Kadagathur, Manasa,Kumar Sigalapalli, Dilep,Nagesh, Narayana,Panda, Biswajit,Phanindranath, Regur,Shankaraiah, Nagula,Sujat Shaikh, Arbaz,Tangellamudi, Neelima D.

, (2022/03/02)

A series of 17 indolo/pyrroloazepinone-oxindole conjugates was synthesized and evaluated for their antiproliferative activity against a panel of selected human cancer cell lines including A549 (lung cancer), HCT116 (colon cancer), MCF7 (breast cancer), and SK-MEL-28 (melanoma). Among the synthesized molecules (14a-m and 15a-d), compound 14d displayed remarkable activity against A549, HCT116 and SK-MEL-28 cells with IC50 values 50 value of 2.33 μM) over the normal rat kidney cells (NRK). Further, 14d-mediated apoptosis affected the cellular and nuclear morphology of the cancer cells in a dose-dependent manner. Wound healing and clonogenic assays inferred the inhibition of cell growth and migration. Target-based studies of compound 14d corroborated its DNA-intercalative capability and Topo I inhibitory activity which have been fortified by molecular modeling studies. Finally, the drug-likeness of the potent compound was determined by performing in silico ADME/T prediction studies.

Synthesis and evaluation of novel anti-proliferative pyrroloazepinone and indoloazepinone oximes derived from the marine natural product hymenialdisine

White, Alex W.,Carpenter, Nicholas,Lottin, Jerome R. P.,McClelland, Richard A.,Nicholson, Robert I.

, p. 246 - 253,8 (2012/12/11)

The tetrahydroazepinone pharmacophore is a component of many interesting compounds, including several marine natural products, with anti-cancer properties. The synthesis and biological evaluation of a novel series of pyrroloazepinone and indoloazepinone oximes is reported. These compounds showed promising growth inhibition activity against four human cancer cell lines but did not significantly inhibit the cell cycle regulator cyclin dependent kinase 2. The most active compounds in this series displayed improved anti-proliferative activity over the related synthetic indoloazepine kenpaullone. The structure activity relationships exhibited by the azepinone pharmacophore suggests several novel lead compounds for anti-cancer drug discovery.

Stereoselective synthesis of (Z)-axino- and (Z)-debromoaxinohydantoin

Tutino, Federico,Posteri, Helena,Borghi, Daniela,Quartieri, Francesca,Mongelli, Nicola,Papeo, Gianluca

experimental part, p. 2372 - 2376 (2009/07/18)

(Z)-Axinohydantoin and (Z)-debromoaxinohydantoin, two pyrrole-imidazole alkaloids isolated from different marine sponges, possess moderate activities in inhibiting the progress of the cell cycle at different phases. A stereoselective synthesis of both nat

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 129053-84-5