130548-06-0 Usage
Description
2(3H)-Thiophenone,3-aminodihydro-, (3R)is a chemical compound characterized by the molecular formula C6H9NOS. It is a derivative of thiophenone, featuring a 3-aminodihydrosubstituent and a specific stereochemistry of (3R)-. 2(3H)-Thiophenone,3-aminodihydro-, (3R)is distinguished by the orientation of its substituent, which may influence its potential applications in various fields.
Uses
Used in Organic Synthesis:
2(3H)-Thiophenone,3-aminodihydro-, (3R)is utilized as a building block in organic synthesis for the creation of complex organic molecules. Its unique structure, including the thiophenone and amine groups, allows for versatile chemical reactions, facilitating the synthesis of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2(3H)-Thiophenone,3-aminodihydro-, (3R)is employed as a precursor in the development of new drugs. 2(3H)-Thiophenone,3-aminodihydro-, (3R)-'s thiophenone and amine functionalities are commonly found in pharmacologically active molecules, making it a valuable component in the design and synthesis of potential therapeutic agents.
Further research and investigation are required to fully explore the potential uses and properties of 2(3H)-Thiophenone,3-aminodihydro-, (3R)-, as its applications may extend beyond the current understanding. Its unique structural features and stereochemistry could offer novel opportunities in both organic synthesis and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 130548-06-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,5,4 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 130548-06:
(8*1)+(7*3)+(6*0)+(5*5)+(4*4)+(3*8)+(2*0)+(1*6)=100
100 % 10 = 0
So 130548-06-0 is a valid CAS Registry Number.
130548-06-0Relevant articles and documents
Cyclization mechanism catalyzed by an ATP-grasp enzyme essential for d-cycloserine biosynthesis
Matoba, Yasuyuki,Uda, Narutoshi,Kudo, Mako,Sugiyama, Masanori
, p. 2763 - 2778 (2020)
In the biosynthetic pathway of an antitubercular antibiotic d-cycloserine (d-CS), O-ureido-d-serine (d-OUS) is converted to d-CS. We have previously demonstrated that DcsG, classified into the ATP-grasp superfamily enzyme, catalyzes the ring formation to generate d-CS, which is accompanied by the cleavage of a bond in the urea moiety of d-OUS to remove a carbamoyl group. Although the general ATP-grasp enzymes catalyze an ATP-dependent ligation reaction between two substrates, DcsG catalyzes specifically the generation of an intramolecular covalent bond. In the present study, cyanate was found in the reaction mixture, suggesting that carbamoyl group is eliminated as an isocyanic acid during the reaction. By the crystallographic and mutational investigations of DcsG, we anticipate the residues necessary for the binding of d-OUS. An acylphosphate intermediate must be bound at the narrow pocket of DcsG in a folded conformation, inducing the bond cleavage and the new bond formation to generate cyanate and d-CS, respectively. Database: Structural data are available in Protein Data Bank database under the accession number 6JIL.
Homocysteine thiolactone as precursor of methionine amide: Application to the modification of peptides of the tachykinin family
Chassaing,Lavielle,Julien,Marquet
, p. 623 - 626 (2007/10/02)
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