13317-11-8 Usage
Chemical class
Quinolone antibiotic derivative
Potential pharmacological properties
Antimicrobial and antiproliferative activities
Target enzyme
Bacterial topoisomerases
Mechanism of action
Inhibition of bacterial topoisomerases, essential for DNA replication and transcription
Antiproliferative effects
Interference with cancer cell DNA replication and cell division processes
Current status
Ongoing research into therapeutic potential
Future applications
Development of new antibiotics and anticancer drugs
Check Digit Verification of cas no
The CAS Registry Mumber 13317-11-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,1 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13317-11:
(7*1)+(6*3)+(5*3)+(4*1)+(3*7)+(2*1)+(1*1)=68
68 % 10 = 8
So 13317-11-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O3/c1-5-2-3-6-8(13)7(10(14)15)4-11-9(6)12-5/h2-4H,1H3,(H,14,15)(H,11,12,13)
13317-11-8Relevant articles and documents
1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors
Manera, Clementina,Betti, Laura,Cavallini, Tiziana,Giannaccini, Gino,Martinelli, Adriano,Ortore, Gabriella,Saccomanni, Giuseppe,Trincavelli, Letizia,Tuccinardi, Tiziano,Ferrarini, Pier Luigi
, p. 4604 - 4610 (2007/10/03)
A series of 1,8-naphthyridine derivatives bearing various substituents in position 3, 4, and 7 of the heterocyclic nucleus have been synthesized and evaluated for their affinity at the bovine and human adenosine receptors. The new compounds were found to