133180-01-5 Usage
Chemical Properties
White to off-white crystalline powder
General Description
The side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphothreonine containing peptides and peptides modified at the threonine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2].The product number for this product was previously 04-12-1141.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Check Digit Verification of cas no
The CAS Registry Mumber 133180-01-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,1,8 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 133180-01:
(8*1)+(7*3)+(6*3)+(5*1)+(4*8)+(3*0)+(2*0)+(1*1)=85
85 % 10 = 5
So 133180-01-5 is a valid CAS Registry Number.
InChI:InChI=1/C38H33NO5/c1-26(44-38(27-15-5-2-6-16-27,28-17-7-3-8-18-28)29-19-9-4-10-20-29)35(36(40)41)39-37(42)43-25-34-32-23-13-11-21-30(32)31-22-12-14-24-33(31)34/h2-24,26,34-35H,25H2,1H3,(H,39,42)(H,40,41)/t26-,35+/m1/s1
133180-01-5Relevant articles and documents
-
Barlos, Kleomenis,Gatos, Dimitrios,Koutsogianni, Sophia,Schaefer, Wolfram,Stavropoulos, George,Wenging, Yao
, p. 471 - 474 (2007/10/02)
The preparation of the N-Fmoc-O-Trt derivatives of serine, threonine and tyrosine is described. Their usefulness in peptide synthesis has been determined in the successful solid phase preparation of the partially protected ACTH (fragment 1-10) and peptide
