133834-03-4 Usage
General Description
2-(4-Hydroxy-2-phenyl-1,3-thiazol-5-yl)acetic Acid is a chemical compound that belongs to the biochemical class of organic compounds known as thiazoles, which are heterocyclic compounds containing a five-member aromatic ring made up of one sulfur atom, one nitrogen atom, and three carbon atoms. This specific compound also contains phenyl and acetic acid groups, with a hydroxy functional group attached to the thiazole ring structure. Its molecular formula is C11H9NO3S and it has a molar mass of 235.26 grams per mole. Despite its structured chemical name, details about its applications or uses in practical scenarios are not readily available, suggesting that it may predominantly be used in academic or industrial research.
Check Digit Verification of cas no
The CAS Registry Mumber 133834-03-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,8,3 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 133834-03:
(8*1)+(7*3)+(6*3)+(5*8)+(4*3)+(3*4)+(2*0)+(1*3)=114
114 % 10 = 4
So 133834-03-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO3S/c13-9(14)6-8-10(15)12-11(16-8)7-4-2-1-3-5-7/h1-5,15H,6H2,(H,13,14)
133834-03-4Relevant articles and documents
4-Hydroxythiazole Inhibitors of 5-Lipoxygenase
Kerdesky, Francis A. J.,Holms, James H.,Moore, Jimmie L.,Bell, Randy L.,Dyer, Richard D.,et al.
, p. 2158 - 2165 (2007/10/02)
4-Hydroxythiazoles have been identified as potent inhibitors of 5-lipoxygenase in vitro exhibiting IC50's of less than 1 μM.An investigation of structure-activity relationships showed that the most potent inhibitors of this series are the 5-phenyl derivatives.The corresponding thiazolidin-4-one analogues were found to be relatively inactive.The 4-hydroxythiazoles were active inhibitors against 5-lipoxygenase in both intact rat polymorphonuclear leukocytes and human whole blood.The compounds were also selective inhibitors of 5-lipoxygenase, displaying only weak activity against other related enzymes, cyclooxygenase and 12- and 15-lipoxygenase.