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133933-76-3

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133933-76-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 133933-76-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,9,3 and 3 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133933-76:
(8*1)+(7*3)+(6*3)+(5*9)+(4*3)+(3*3)+(2*7)+(1*6)=133
133 % 10 = 3
So 133933-76-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO2S/c9-5-6(4-8(10)11)7-2-1-3-12-7/h1-3,6H,4-5,9H2,(H,10,11)

133933-76-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-3-thiophen-2-ylbutanoic acid

1.2 Other means of identification

Product number -
Other names 4-Amino-3-(2-thienyl)butanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133933-76-3 SDS

133933-76-3Downstream Products

133933-76-3Relevant articles and documents

METHODS OF TREATING FRAGILE X SYNDROME, DOWN?S SYNDROME, AUTISM AND RELATED DISORDERS

-

, (2012/02/01)

Disclosed herein are methods of treating fragile X syndrome, fragile X-associated tremor/ataxia syndrome, Down?s syndrome and other forms of mental retardation, and/or autism comprising administering a GABA B agonist prodlug to a subject suffering therefrom. The GABAB agonist prodrugs can be compounds of Formula (I), (II) or (III) as disclosed herein

3-thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABA(B) receptor studies

Berthelot,Vaccher,Flouquet,Debaert,Luyckx,Brunet

, p. 2557 - 2560 (2007/10/02)

Baclofen (β-(p-chlorophenyl)-GABA) is a selective agonist for the bicuculline-insensitive GABA(B) receptor. The search for new compounds that bind to the GABA(B) receptor is very important to clarify structural requirements. We report herein the synthesis and the binding studies of variously substituted 3-thienyl- and 3-furylaminobutyric acids. 4-Amino-3-(5-methyl-2-thienyl)butyric acid (5d) and 4-amino-3-(5-chloro-2-thienyl)butyric acid (5h) are potent and specific ligands for GABA(B) receptor. The IC50 values for the displacement of (R)-(-)-[3H]baclofen are 1.34 and 0.61 μM for 5d and 5h, respectively, as compared to 0.33 μM for baclofen.

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