134444-47-6

• 

• Basic information

  1. Product Name: 2-Amino-2'-deoxy-2'-fluoro-D-adenosine
  2. Synonyms: 2-Amino-2'-deoxy-2'-fluoro-D-adenosine;Adenosine, 2-aMino-2'-deoxy-2'-fluoro-;2-AMino-2'-fluoro-2'-deoxyadenosine;2,6-Diamino-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine
  3. CAS NO:134444-47-6
  4. Molecular Formula: C₁₀H₁₃FN₆O₃
  5. Molecular Weight: 284.25
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 134444-47-6.mol
  9. Article Data: 7

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: White to Off-white/Powder
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
  8. Solubility: N/A
  9. CAS DataBase Reference: 2-Amino-2'-deoxy-2'-fluoro-D-adenosine(CAS DataBase Reference)
  10. NIST Chemistry Reference: 2-Amino-2'-deoxy-2'-fluoro-D-adenosine(134444-47-6)
  11. EPA Substance Registry System: 2-Amino-2'-deoxy-2'-fluoro-D-adenosine(134444-47-6)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 134444-47-6(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

134444-47-6 Suppliers

Recommended suppliersmore

• Product
• FOB Price
• Min.Order
• Supply Ability
• Supplier
• Contact Supplier

• 2-Amino-2'-deoxy-2'-fluoro-D-adenosine CAS：134444-47-6

  Cas No: 134444-47-6

• USD $ 150.0-200.0 / Kilogram

• 1 Kilogram

• 200 Metric Ton/Day

• Hebei Nengqian Chemical Import and Export Co., LTD
• Contact Supplier

• 2'-Amino-2'-deoxy-2-fluoroadenosine

  Cas No: 134444-47-6

• No Data

• No Data

• No Data

• Dayang Chem (Hangzhou) Co.,Ltd.
• Contact Supplier

• Adenosine,2-amino-2'-deoxy-2'-fluoro- (9CI)

  Cas No: 134444-47-6

• No Data

• No Data

• 10000 Metric Ton/Month

• Henan Wentao Chemical Product Co., Ltd.
• Contact Supplier

• 2-?amino-?2'-?deoxy-?2'-?fluoro-Adenosine

  Cas No: 134444-47-6

• No Data

• 1 Milligram

• Kilogram/Month

• NewCan Biotech Limited
• Contact Supplier

• 2-Amino-2'-F-2'-deoxy-adenosine

  Cas No: 134444-47-6

• No Data

• 100 Gram

• 100 Metric Ton/Year

• Wuhu Nuowei Chemistry Technologies Co., Ltd.
• Contact Supplier

• 2-Amino-2'-Fluoro-2'-Deoxyadenosine

  Cas No: 134444-47-6

• No Data

• No Data

• No Data

• HANGZHOU TIANYE CHEMICALS CO., LTD.
• Contact Supplier

• 2-AMINO-2'-DEOXY-2'-FLUORO-D-ADENOSINE

  Cas No: 134444-47-6

• No Data

• No Data

• No Data

• Hangzhou Fandachem Co.,Ltd
• Contact Supplier

• Adenosine, 2-amino-2'-deoxy-2'-fluoro-

  Cas No: 134444-47-6

• No Data

• No Data

• No Data

• SAGECHEM LIMITED
• Contact Supplier

• 2-Amino-2'-fluoro-2'-deoxyadenosine

  Cas No: 134444-47-6

• No Data

• No Data

• No Data

• Shanghai Yuanye Bio-Technology Co., Ltd.
• Contact Supplier

• (2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

  Cas No: 134444-47-6

• No Data

• No Data

• No Data

• Chemlyte Solutions
• Contact Supplier

134444-47-6 Usage

General Description

2-Amino-2'-deoxy-2'-fluoro-D-adenosine, also known as 2'-F-adenosine, is a synthetic analogue of adenosine with potent anti-cancer activities. The presence of the Fluorine atom at the 2' position on the ribose sugar makes this compound resistant to adenosine deaminase, an enzyme that breaks down adenosine. As a result, it inhibits cell proliferation and induces apoptosis in cancer cells. Due to its pharmacological efficiency and stability, this compound has been utilized in the development of several anticancer drugs and therapies. However, like all medicines, it may also carry potential side effects and risks. In general, this chemical is significant in medical research and therapeutic developments for its potential anticancer properties.

Check Digit Verification of cas no

The CAS Registry Mumber 134444-47-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,4,4 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 134444-47:
(8*1)+(7*3)+(6*4)+(5*4)+(4*4)+(3*4)+(2*4)+(1*7)=116
116 % 10 = 6
So 134444-47-6 is a valid CAS Registry Number.

134444-47-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	(2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

1.2 Other means of identification

Product number	-
Other names	2-Amino-2'-deoxy-2'-fluoroadenosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:134444-47-6 SDS

134444-47-6Upstream product

• 5451-40-1 2,6-dichloro-7H-purine 
• 52826-86-5 1,6-diaminopurine 
• 1904-98-9 2,6-diaminopurine 
• 156357-16-3 2,6-dichloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-ribofuranosyl)purine 
• 156357-13-0 2,6-diazido-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-ribofuranosyl)purine 
• 149623-91-6 1-O-acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-ribofuranoside 
• 10212-20-1 2'-deoxy-2'-fluorocytidine 
• 56287-17-3 2'-deoxy-2'-fluorouridine 
• 156357-14-1 2,6-diamino-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-ribofuranosyl)purine 

134444-47-6Downstream Products

• 78842-13-4 2'-deoxy-2'-fluoroguanosine 
• 147048-53-1 2'-Deoxy-2,2'-difluoro-adenosine 
• 1431557-60-6 2-amino-2’-fluoro-2’-deoxyadenosine-5’-O-naphthyl(benzoxy-L-alaninyl)phosphate 
• 1431557-61-7 2-amino-2’-fluoro-2’-deoxyadenosine-5’-O-naphthyl(cyclohexoxy-L-alaninyl)phosphate 
• 1431557-63-9 2-amino-2’-fluoro-2’-deoxyadenosine-5’-O-phenyl(benzoxy-L-alaninyl)phosphate 
• 1431557-64-0 2-amino-2’-fluoro-2’-deoxyadenosine-5’-O-phenyl(cyclohexoxy-L-alaninyl)phosphate 
• 1431557-65-1 2-amino-2’-fluoro-2’-deoxyadenosine-5’-O-phenyl(ethoxy-L-alaninyl)phosphate 

134444-47-6Relevant articles and documents

Chemical and enzymatic synthesis and antiviral properties of 2'-deoxy- 2'-fluoroguanosine

Zaitseva, Galina V.,Zinchenko, Anatoli I.,Barai, Vladimir N.,Pavlova,Boreko, Evgeny I.,Mikhailopulo, Igor A.

, p. 687 - 688 (1999)

Chemical and enzymatic methods were employed for the synthesis of the title compound, 2'F-Guo 7. High antiviral activity of 2'F-Guo was established in chick embryo cells infected with influenza virus FPV/Rostock/34 (H7N1) and herpes simplex virus (HSV) type I (1C strain).

Anti-HCV nucleoside derivatives

-

, (2008/06/13)

The present invention comprises nucleoside derivatives for use in the treatment or prophylaxis of hepatitis C virus infections. In particular, the present invention discloses the novel use of known 2'-deoxy-2'-fluoro nucleoside derivatives as inhibitors of hepatitis C virus (HCV) RNA replication and pharmaceutical compositions of such compounds. The compounds of this invention have potential use as therapeutic agents for the treatment of HCV infections.

Synthesis and biologic activity of purine 2'-deoxy-2'-fluoro- ribonucleosides

Thomas,Tiwari,Clayton,Secrist III,Montgomery

, p. 309 - 323 (2007/10/02)

The synthesis of 3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-ribofuranosyl bromide (8) and its reaction with 2,6-dichloropurine by fusion and with mercuric cyanide catalysis is described. The resulting 2,6-dichloro-9-(3,5-di-O- benzoyl-2-deoxy-2-fluoro-β-D-ribofuranosyl)purine (13) was converted to the 2-fluoroadenine (16), the 2-chloroadenine (17), 2,6-diaminopurine (12), and guanine (14) nucleosides by standard procedures. These nucleosides were cytotoxic to a number of cell lines in culture. The 2-haloadenine nucleosides 16 and 17 gave modest increases in lifespan when tested against the P388 leukemia in mice.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 134444-47-6 2-Amino-2'-deoxy-2'-fluoro-D-adenosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send