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13528-13-7

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13528-13-7 Usage

Description

1-(2,3-dimethylphenyl)-3-phenylthiourea, commonly known as dimethipin, is a chemical compound belonging to the thiourea class. It is characterized by its molecular formula C15H15N3S and is recognized for its diverse biological activities and potential applications across various industries.

Uses

Used in Agricultural Applications:
Dimethipin is used as a pesticide and plant growth regulator in the agricultural industry. It is particularly effective due to its ability to inhibit the biosynthesis of gibberellins, which are plant hormones that control growth and development. This property makes dimethipin a valuable tool for managing plant growth and protecting crops from pests.
Used in Pharmaceutical Applications:
Dimethipin is also being investigated for its potential as an antifungal and antimicrobial agent in the pharmaceutical industry. Its ability to combat fungal and microbial infections could lead to new treatments and therapies for various diseases and conditions.
As a chemical with potential implications for both agricultural and pharmaceutical industries, dimethipin continues to be an area of ongoing research and development, aiming to unlock its full potential and maximize its benefits in these sectors.

Check Digit Verification of cas no

The CAS Registry Mumber 13528-13-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,2 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13528-13:
(7*1)+(6*3)+(5*5)+(4*2)+(3*8)+(2*1)+(1*3)=87
87 % 10 = 7
So 13528-13-7 is a valid CAS Registry Number.

13528-13-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,3-dimethylphenyl)-3-phenylthiourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13528-13-7 SDS

13528-13-7Downstream Products

13528-13-7Relevant articles and documents

Inhibition of adipogenesis by thiourea derivatives

Siddiqui, Hina,Shafi, Sarah,Mukhtar, Farah,Ejaz, Asma,Atta-Ur-Rahman,Choudhary, M. Iqbal

, p. 508 - 515 (2018/07/25)

Background: Obesity is one of the major health problems with inherent risk of type 2 diabetes, hypertension, CVDs, etc. Adipogenesis is a major contributor in the process of obesity. Inhibition of adipocytes differentiation is one of the key approaches to treat obesity. Objective: To discover the new inhibitors of adipogenesis as the treatment for obesity. Method: We describe here, the synthesis, and anti-adipogenic activity of thiourea derivatives 1-14. These derivatives were synthesized by the reactions of phenyl and pentafluorophenyl isothiocyanate with different aromatic amines. Pure compounds 1-14 were evaluated for their in vitro antiadipogenesis activity employing 3T3-L1 cells lines. Results: Compounds 1-3, 5-9, and 11-14 significantly inhibited the pre-adipocyte differentiation into adipocytes, which was measured by staining the cells, and through morphological examination. Compound 10 (1-(4"-Chlorophenyl)-3-(pentafluorophenyl)-thiourea) showed a potent inhibition of adipocyte differentiation with IC50 = 740.00 ± 2.36 nM, which was more potent than the standards, epigallocatechin gallate (IC50 = 16.73 ± 1.34 μM), and curcumin (IC50 = 18.62 ± 0.74 μM). All other compounds showed a moderate to weak anti-adipogenesis activity. Compounds 1- 14 were also evaluated for their cytotoxicity. Compounds 3, 10, and 14 showed some toxicity to the cancer cell lines, while compounds 2, 3, 10, 12, and 14 showed a moderate to weak cytotoxicity against the normal cell lines. Conclusion: All the compounds reported in this paper are known, except compound 11. They have been identified as new inhibitors of Adipogenesis. Adipogenesis is the process of adipocytes differentiation from pre-adipocytes. This extensively studied model of cell diff differentiation. Further synthetic modifications, and optimization of anti-adipogenic activity may lead to the development of anti-obesity agents.

Inhibition of brain respiration by new anticonvulsant benzylidene thiobarbiturates

Gupta,Gupta,Bhargava,Ali

, p. 448 - 452 (2007/10/02)

The present study describes the synthesis of eleven new 1-phenyl-3-(2',3'-dimethylphenyl)-5-(substituted benzylidene) thiobarbiturates and their anticonvulsant property. All compounds, at a final dose of 100 mg/kg, protected mice against pentylenetetrazol

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