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135367-08-7

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135367-08-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 135367-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,3,6 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 135367-08:
(8*1)+(7*3)+(6*5)+(5*3)+(4*6)+(3*7)+(2*0)+(1*8)=127
127 % 10 = 7
So 135367-08-7 is a valid CAS Registry Number.

135367-08-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (1S,3S,4S,5R)-3-(4-bromophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

1.2 Other means of identification

Product number -
Other names RTI-51

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:135367-08-7 SDS

135367-08-7Relevant articles and documents

Fluoralkenyl nortropanes

-

Page column 16, (2008/06/13)

Provided are compounds of the following formula: wherein R is C2-C6 mono- or multi-unsaturated hydrocarbon having one or more ethylene, acetylene or allene groups, A is 18 or 19, and X is H or halogen. The compounds of the invention bind to dopamine transporter with high affinity and selectivity and are thus useful as diagnostic and therapeutic agents for diseases associated with dopamine transporter dysfunction. The radiolabeled compounds are useful as imaging agents for visualizing the location and density of dopamine transporter by PET imaging.

Synthesis, in vitro characterization and ex vivo evaluation 2β-carbomethoxy-3β-(4-fluoroalkyl-3-halophenyl)nortropanes: New potential SERT imaging agents for PET or SPECT

Chen,Kilts,Camp,Ely,Malveaux,Votaw,Hoffman,Goodman

, p. S324-S326 (2007/10/03)

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Synthesis, ligand binding, QSAR, and CoMFA study of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters

Carroll,Gao,Rahman,Abraham,Parham,Lewin,Boja,Kuhar

, p. 2719 - 2725 (2007/10/02)

A series of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters (2) were synthesized and found to possess high affinity for the cocaine binding site in rat striatum. The p-chloro (2c) and p-iodo (2n) compounds, which were the most potent analogues prepared, were found to be 85 and 78 times more potent than (-)-cocaine. The p-bromo (2m) and p-methyl (2d) were also 56 and 60 times more potent than cocaine. QSAR and CoMFA studies were conducted to correlate binding affinity of the cocaine analogues with their structural features. Whereas the QSAR study gave relatively low correlations, the CoMFA study gave a correlation with high predictive value.

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