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137730-67-7

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137730-67-7 Usage

General Description

Spiro[indene-1,4'-piperidine] hydrochloride is a chemical compound with the molecular formula C19H21ClN. It is a spiro compound, meaning that it contains two rings that share a single carbon atom. spiro[indene-1,4'-piperidine] hydrochloride has been studied for its potential use in pharmaceuticals, especially in the development of new drugs targeting central nervous system disorders. It is also being investigated for its potential as an anti-inflammatory agent. Spiro[indene-1,4'-piperidine] hydrochloride is a complex compound with potential therapeutic applications, and its properties continue to be studied in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 137730-67-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,7,3 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 137730-67:
(8*1)+(7*3)+(6*7)+(5*7)+(4*3)+(3*0)+(2*6)+(1*7)=137
137 % 10 = 7
So 137730-67-7 is a valid CAS Registry Number.

137730-67-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Spiro[indene-1,4'-piperidine] hydrochloride

1.2 Other means of identification

Product number -
Other names spiro[indene-1,4'-piperidine],hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:137730-67-7 SDS

137730-67-7Relevant articles and documents

Serine derivatives and their use as therapeutic agents

-

, (2008/06/13)

The present invention relates to compounds of formula (I): STR1 wherein m is zero, 1 or 2; and n is zero or 1, with the proviso that the sum total of m+n is 1 or 2; R1 represents phenyl; naphthyl; benzhydryl; or benzyl, where the naphthyl group or any phenyl moiety may be substituted; R2 represents hydrogen; phenyl; heteroaryl selected from indazolyl, thienyl, furanyl, pyridyl, thiazolyl, tetrazolyl and quinolinyl; naphthyl; benzhydryl; or benzyl; wherein each heteroaryl, the naphthyl group and any phenyl moiety may be substituted; R3 and R4 each independently represents hydrogen or C1-6 alkyl or R3 and R4 together are linked so as to form a C1-3 alkylene chain; Q represents CR5 R6 or NR5 ; X and Y each independently represents hydrogen, or together form a group =O; and Z represents a bond, O, S, SO, SO2, NRc or --(CRc Rd)--, where Rc and Rd each independently represent hydrogen or C1-6 alkyl; or a pharmaceutically acceptable salt thereof. The compounds are of particular use in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.

Piperidinylcamphorsulfonyl oxytocin antagonists

-

, (2008/06/13)

Spirocyclic compounds of the formula: are oxytocin and vasopressin antagonists useful in the treatment of pre-term labor, dysmenorrhea and for the stoppage of labor preparatory to cesarean delivery, timing of parturition, uterine hyperactivity, endometriosis, hypertension, congestive heart failure, hyponatremia and cognitive disorders.

Orally Active, Nonpeptide Oxytocin Antagonists

Evans, Ben E.,Leighton, James L.,Rittle, Kenneth E.,Gilbert, Kevin F.,Lundell, George F.,et al.

, p. 3919 - 3927 (2007/10/02)

The first nonpeptide antagonists of the neurohypophyseal hormone, oxytocin (OT) are described.Derivatives of the spiroindenepiperidine ring system, these compounds include L-366,509, an orally bioavailable OT antagonist with good in vivo duration.The potential use of these agents for treatment of preterm labor and their significance as new nonpeptide ligands for peptide receptors are discussed.

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