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138457-39-3

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138457-39-3 Usage

Chemical classification

Ketone

Physical form

White crystalline powder

Primary use

Intermediate in the synthesis of pharmaceuticals and other organic compounds

Secondary uses

Reagent in chemical research, ingredient in the production of agrochemicals, and intermediate in the production of pesticides and insecticides

Notable properties

High purity and relatively low toxicity

Importance

Key component in various industrial and research processes

Check Digit Verification of cas no

The CAS Registry Mumber 138457-39-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,4,5 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 138457-39:
(8*1)+(7*3)+(6*8)+(5*4)+(4*5)+(3*7)+(2*3)+(1*9)=153
153 % 10 = 3
So 138457-39-3 is a valid CAS Registry Number.

138457-39-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloro-1-(2,4-difluorophenyl)-1-propanone

1.2 Other means of identification

Product number -
Other names 1-PROPANONE,2-CHLORO-1-(2,4-DIFLUOROPHENYL)-,(S)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:138457-39-3 SDS

138457-39-3Downstream Products

138457-39-3Relevant articles and documents

Synthesis and biological evaluation of vinyl ether-containing azole derivatives as inhibitors of Trichophyton rubrum

Wang, Lulu,Yang, Wenge,Wang, Kai,Zhu, Jing,Shen, Fei,Hu, Yonghong

scheme or table, p. 4887 - 4890 (2012/08/07)

In an attempt to search for many target compounds with excellent activities, a series of vinyl ether-containing azole derivatives were designed, synthesized, and evaluated as antifungal agents. Results of preliminary antifungal tests against Trichophyton rubrum in vitro indicated that most of the synthesized compounds showed excellent activities. In comparison with fluconazole, itraconazole, voriconazole, omoconazole and amphotericin B, several compounds (such as 7d, 7g and 7h) exhibited more potent inhibitory activities, suggesting that they were promising leads for the development of novel antifungal agents.

Azole compounds as therapeutic agents for fungal infections

-

Page column 32-33, (2010/02/05)

The present invention relates to the derivatives of specially substituted azole compounds which have improved antifungal activity as compared to known compounds such as fluconazole and itraconazole and the processes for the preparation thereof. This invention also relates to pharmaceutical compositions containing the compounds of the present invention and their use in treating and/or preventing fungal infections in mammals, preferably humans.

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