138560-08-4 Usage
Description
Uridine, 2'-deoxy-4'-thio-, 5'-acetate is a chemically modified nucleoside derived from uridine, a naturally occurring nucleoside that plays a crucial role in various biological processes. Uridine, 2'-deoxy-4'-thio-, 5'-acetate features a 2'-deoxy-4'-thio modification, where the oxygen atom in the sugar moiety of uridine is replaced with a sulfur atom, and a 5'-acetate group, which adds an acetyl group to the 5' position of the nucleoside. These modifications can potentially enhance the biological activity and stability of uridine, making it a valuable tool in research and pharmaceutical applications for studying and modulating nucleoside function in biological systems.
Uses
Used in Pharmaceutical Research:
Uridine, 2'-deoxy-4'-thio-, 5'-acetate is used as a research compound for investigating the role of nucleosides in various biological processes. The chemical modifications in this compound can provide insights into the structure-activity relationships of nucleosides and their interactions with enzymes, receptors, and other biomolecules.
Used in Drug Development:
Uridine, 2'-deoxy-4'-thio-, 5'-acetate can be employed as a lead compound in the development of novel therapeutic agents targeting specific biological pathways or diseases. The unique chemical properties of this compound may offer advantages in terms of selectivity, potency, and pharmacokinetics compared to naturally occurring nucleosides.
Used in Biochemical Assays:
This modified nucleoside can be utilized in various biochemical assays to study enzyme activity, substrate specificity, and reaction mechanisms. The 2'-deoxy-4'-thio and 5'-acetate modifications may provide unique opportunities to probe enzyme-substrate interactions and develop new assay methodologies.
Used in Nucleic Acid Synthesis:
Uridine, 2'-deoxy-4'-thio-, 5'-acetate can be incorporated into synthetic nucleic acids, such as DNA or RNA, to investigate the effects of these modifications on nucleic acid structure, stability, and function. This can be particularly useful in the development of antisense oligonucleotides, aptamers, or other nucleic acid-based therapeutics.
Used in Chemical Biology:
This modified nucleoside can be employed as a chemical probe in chemical biology to study the interactions between nucleosides and their target proteins or other biomolecules. The unique chemical properties of Uridine, 2'-deoxy-4'-thio-, 5'-acetate may enable the discovery of novel biological targets or the elucidation of molecular mechanisms underlying various biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 138560-08-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,5,6 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 138560-08:
(8*1)+(7*3)+(6*8)+(5*5)+(4*6)+(3*0)+(2*0)+(1*8)=134
134 % 10 = 4
So 138560-08-4 is a valid CAS Registry Number.
