138944-33-9Relevant articles and documents
Ring transformation mediated by Lewis acids and oxidizing agents. Synthesis of 2-methoxy-1H-imidazole from 5-aminopyrimidin-4(3H)-one
Matsuura,Ueda,Murakami,Nagai,Sakakibara
, p. 608 - 610 (1993)
Treatment of 5-aminopyrimidin-4(3H)-one (1) with Lewis acidic metal salts such as zinc chloride, zinc bromide, zinc iodide, aluminum chloride, aluminum bromide, nickel chloride, copper(I) chloride, or copper(I) iodide in the presence of oxidizing agents such as ceric ammonium nitrate, ammonium persulfate, or phenyliodine(III) diacetate in methanol gave 2-methoxy-1H-imidazole (2).
A Facile Ring Transformation of 5-Aminopyrimidin-4(3H)-one into 2-Alkoxy-1H-imidazoles in the Presence of Oxidative Metal Salts and Alkyl Alcohols
Matsuura, Izumi,Ueda, Taisei,Murakami, Nobutoshi,Nagai, Shin-ichi,Sakakibara, Jinsaku
, p. 1688 - 1689 (2007/10/02)
5-Amino-6-methyl-3-phenylpyrimidin-4(3H)-one 1 was transformed into 2-alkoxy-1H-imidazoles 2a-f by treatment with various oxidative metals salts such as CuCl2, CuBr2, Cu(NO3)2, CuSO4, Tl(NO3)3, FeCl3 and Pb(OAc)4 in alkyl alcohols.