1396257-94-5
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Basic information
- Product Name: GDC 0068 (Hydrochloride)
- Synonyms: GDC 0068 (Hydrochloride);GDC-0068 dihydrochloride;(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one dihydrochloride;Ipatasertib dihydrochloride;RG-7440 dihydrochloride;GDC0068 2HCl;Ipatasertib (GDC-0068) 2HCl
- CAS NO:1396257-94-5
- Molecular Formula: C24H34Cl3N5O2
- Molecular Weight: 530.91806
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1396257-94-5.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: GDC 0068 (Hydrochloride)(CAS DataBase Reference)
- NIST Chemistry Reference: GDC 0068 (Hydrochloride)(1396257-94-5)
- EPA Substance Registry System: GDC 0068 (Hydrochloride)(1396257-94-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1396257-94-5(Hazardous Substances Data)
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1396257-94-5 Usage
General Description
Ipatasertib dihydrochloride is a small molecule inhibitor that belongs to the class of biarylureas. It is specifically designed to target and inhibit the activity of the protein kinase Akt, which is involved in various cellular processes including cell survival, proliferation, and metabolism. The dihydrochloride salt form of ipatasertib makes it water-soluble and suitable for use in aqueous solutions. Ipatasertib dihydrochloride has shown promising results in preclinical and clinical studies as a potential anti-cancer agent, particularly in cancers with genetic alterations in the PI3K/Akt pathway. It is currently being investigated in clinical trials for its efficacy in treating various types of cancer, including breast, prostate, and ovarian cancer.Check Digit Verification of cas no
The CAS Registry Mumber 1396257-94-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,6,2,5 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.Calculate Digit Verification of CAS Registry Number 1396257-94:
(9*1)+(8*3)+(7*9)+(6*6)+(5*2)+(4*5)+(3*7)+(2*9)+(1*4)=205
205 % 10 = 5
So 1396257-94-5 is a valid CAS Registry Number.
1396257-94-5Upstream product
1396257-94-5Downstream Products
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GDC 0068 (Hydrochloride)
