139756-01-7

• 

• Basic information

  1. Product Name: 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide
  2. Synonyms: 1-methyl-4-nitro-3-propyl-(1h)-pyrazole-5-carboxamide;1-Methyl-3-Propyl-4-Nitro-5-Carboxamide Pyrazole;1-Methyl-3-Propyl-4-Nitro-5-Carboxamide-(1H)-Pyrazole;2-methyl-4-nitro-5-propylpyrazole-3-carboxamide;1H-Pyrazole-5-carboxamide,1-methyl-4-nitro-3-propyl-;1-methyl-4-nitro-3-propyl-1H-5-pyrazole carboxamide
  3. CAS NO:139756-01-7
  4. Molecular Formula: C₈H₁₂N₄O₃
  5. Molecular Weight: 212.20588
  6. EINECS: N/A
  7. Product Categories: Erectile Dysfunction;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
  8. Mol File: 139756-01-7.mol
  9. Article Data: 16

• Chemical Properties

  1. Melting Point: 137.0 to 141.0 °C
  2. Boiling Point: 334.559 °C at 760 mmHg
  3. Flash Point: 156.136 °C
  4. Appearance: /
  5. Density: 1.453 g/cm³
  6. Vapor Pressure: 0.000127mmHg at 25°C
  7. Refractive Index: 1.629
  8. Storage Temp.: Sealed in dry,Room Temperature
  9. Solubility: soluble in Methanol
  10. PKA: 14.62±0.50(Predicted)
  11. CAS DataBase Reference: 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide(CAS DataBase Reference)
  12. NIST Chemistry Reference: 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide(139756-01-7)
  13. EPA Substance Registry System: 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide(139756-01-7)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 139756-01-7(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

139756-01-7 Suppliers

Recommended suppliersmore

• Product
• FOB Price
• Min.Order
• Supply Ability
• Supplier
• Contact Supplier

• Factory Supply 1-methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxamide

  Cas No: 139756-01-7

• No Data

• 1

• 1

• Ality Chemical Corporation
• Contact Supplier

• 1-Methyl-4-Nitro-3-Propyl- (1H) -Pyrazole-5-Carboxamide

  Cas No: 139756-01-7

• No Data

• 1 Metric Ton

• 1 million Metric Ton/Year

• COLORCOM LTD.
• Contact Supplier

• 1-METHYL-4-NITRO-3-PROPYL-(1H)-PYRAZOLE-5-CARBOXAMIDE

  Cas No: 139756-01-7

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
• Contact Supplier

• 1-Methyl-4-nitro-3-propyl-5(1H)-pyrazolecarboxamide

  Cas No: 139756-01-7

• USD $ 1.2-5.0 / Kiloliter

• 5 Kiloliter

• 3000 Metric Ton/Month

• Chemwill Asia Co., Ltd.
• Contact Supplier

• TIANFUCHEM--139756-01-7--High purity 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide

  Cas No: 139756-01-7

• USD $ 2000.0-2000.0 / Metric Ton

• 1 Metric Ton

• 1000 Metric Ton/Day

• Henan Tianfu Chemical Co., Ltd.
• Contact Supplier

• Factory direct supply CAS 139756-01-7 with best quality

  Cas No: 139756-01-7

• USD $ 139.0-210.0 / Kilogram

• 1 Kilogram

• 1000 Kilogram/Day

• Zhuozhou Wenxi import and Export Co., Ltd
• Contact Supplier

• 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide

  Cas No: 139756-01-7

• USD $ 80.0-100.0 / Kilogram

• 10 Kilogram

• 10 Metric Ton/Month

• Wuhan Han Sheng New Material Technology Co.，Ltd
• Contact Supplier

• 1-METHYL-4-NITRO-3-PROPYL-(1H)-PYRAZOLE-5-CARBOXAMIDE High purity

  Cas No: 139756-01-7

• No Data

• No Data

• Metric Ton/Day

• Antimex Chemical Limied
• Contact Supplier

• 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide/ LIDE PHARMA- Factory supply / Best price

  Cas No: 139756-01-7

• No Data

• No Data

• 1

• LIDE PHARMACEUTICALS LIMITED
• Contact Supplier

• 1-methyl-4-nitro-3-propyl-(1h)-pyrazole-5-carboxamide

  Cas No: 139756-01-7

• No Data

• 10 Gram

• 500 Kilogram/Month

• Wuhan Wonda Pharm Limited
• Contact Supplier

139756-01-7 Usage

Chemical Properties

Off-White to Light Brown Solid

Uses

Intermediate in the production of Sildenafil.

Check Digit Verification of cas no

The CAS Registry Mumber 139756-01-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,7,5 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 139756-01:
(8*1)+(7*3)+(6*9)+(5*7)+(4*5)+(3*6)+(2*0)+(1*1)=157
157 % 10 = 7
So 139756-01-7 is a valid CAS Registry Number.

InChI:InChI=1/C8H12N4O3/c1-3-4-5-6(12(14)15)7(8(9)13)11(2)10-5/h3-4H2,1-2H3,(H2,9,13)

139756-01-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-methyl-4-nitro-5-propylpyrazole-3-carboxamide

1.2 Other means of identification

Product number	-
Other names	1-methyl-4-nitro-3-propyl-1H-5-pyrazole carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:139756-01-7 SDS

139756-01-7Upstream product

• 139756-00-6 1-methyl-2-nitro-3-propyl-1H-pyrazole-5-carboxylic acid 
• 92945-27-2 ethyl 3-propyl-1H-pyrazole-5-carboxylate 
• 107-87-9 2-Pentanone 
• 133261-07-1 1-Methyl-3-n-propylpyrazole-5-carboxylic acid ethyl ester 
• 139755-99-0 1-methyl-3-propyl-1 H-pyrazole-5-carboxylic acid 
• 36983-31-0 ethyl 3-butyrylpyruvate 
• 360068-47-9 1-methyl-4-nitro-3-propyl-1H-pyrazole-5-carbonyl chloride 

139756-01-7Downstream Products

• 200575-15-1 4-[2-ethoxy-5-(4-methyl-1-piperazinylsulphonyl)benzamido]-1-methyl-3-propyl-1H-pyrazole-5-carboxamide 

139756-01-7Relevant articles and documents

A new process for the synthesis of sildenafil intermediate and resulting sildenafil intermediates (by machine translation)

-

Paragraph 0044; 0052-0058, (2019/06/07)

The present invention discloses a new process for the synthesis of sildenafil intermediate and resulting sildenafil intermediate, which belongs to the technical field of pharmaceutical intermediates. The invention comprises the following steps: S1: nitration reaction to 1 - methyl - 3 - propyl pyrazole - 5 - carboxylic acid ethyl ester as the starting material, adopts concentrated sulfuric acid and concentrated nitric acid to the starting material to nitration, shall nitration product; S2: amidation reaction uses ammonium chloride and trimethyl aluminum of the nitration reagent to the aminolysis product aminolysis, quenching, separation, drying, evaporation of the solvent, shall be sildenafil intermediate 1 - methyl - 3 - propyl - 4 - nitryl pyrazole - 5 - carboxamide. The invention from an initial raw material to the target product only needing two-step reaction can be completed, the process flow is short, mild condition, a substantial increase in product yield, save a large number of strong acid, strong alkali and thionyl chloride and other inorganic irritation raw materials, will not cause corrosion of the apparatus, to reduce the large amount of waste water and waste acid, reduce the environmental pressure. (by machine translation)

NOVEL COMPOUNDS FOR USE IN COGNITION IMPROVEMENT

-

, (2016/04/19)

Novel compounds for use in cognition improvement It relates to certain compounds having a polycyclic structure and a -(C=O)NRaRb moiety, wherein the polycyclic structure comprises at least three ring systems, wherein one ring system is a polycyclic ring system comprising from 2 to 4 rings; at least one ring is an aromatic ring; and wherein the structure comprises at least 3 nitrogen atoms and 1 oxygen atom. It also relates to pharmaceutical compositions containing them, and to their use in medicine, in particular in the treatment and/or prevention of neurological disorders coursing with a cognition deficit or impairment, or neurodegenerative diseases.

PYRAZOLOPYRIMIDINONES FOR THE TREATMENT OF IMPOTENCE AND PROCESS FOR THE PREPARATION THEREOF

-

Page/Page column 47, (2015/09/23)

The present invention relates to Pyrazolopyrimidinone compounds as PDE5 inhibitors with better IC50 value, good in vivo efficacy and PK profile and a process for the preparation thereof. The present invention covers the pyrazolo pyrimidinone based compounds that have been designed, synthesized and screened for PDE5 inhibitory activity and its PDE5 inhibitory potential is provided in this invention. These designer compounds have shown nanomolar potency when screened for PDE5 inhibitory activity and also shown better in vivo efficacy. These compounds can be used in the treatment of male erectile dysfunction or in the treatment of impotence.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 139756-01-7 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send