14141-47-0 Usage
Uses
MRS 2219 is a cyclic pyridoxine-alpha4, 5-monophosphate compound.
Biological Activity
A selective potentiator of ATP-evoked responses at rat P2X 1 receptors (EC 50 = 5.9 μ M).
Check Digit Verification of cas no
The CAS Registry Mumber 14141-47-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,4 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14141-47:
(7*1)+(6*4)+(5*1)+(4*4)+(3*1)+(2*4)+(1*7)=70
70 % 10 = 0
So 14141-47-0 is a valid CAS Registry Number.
14141-47-0Relevant articles and documents
A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors
Jacobson, Kenneth A.,Kim, Yong-Chul,Wildman, Scott S.,Mohanram, Arvind,Harden, T. Kendall,Boyer, José L.,King, Brian F.,Burnstock, Geoffrey
, p. 2201 - 2206 (1998)
Analogues of the P2 receptor antagonists pyridoxal-5'-phosphate and the 6-azophenyl-2',4'-disulfonate derivative (PPADS), in which the phosphate group was cyclized by esterification to a CH2OH group at the 4-position, were synthesized. The cycl