142102-79-2 Usage
General Description
The chemical "1-(2',5'-bis-O-(tert-butyldimethylsilylribofuranosyl)-3-N-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)" is a nucleoside analogue with potential antiviral activity. It consists of a ribonucleoside analog linked to a spirocyclopropyl oxathiole dioxide, which contains a thymine base and a methyl group. 1-(2',5'-bis-O-(tert-butyldimethylsilylribofuranosyl)-3-N-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) has been studied for its potential use in antiviral therapy, particularly against DNA viruses. It can inhibit viral DNA replication by acting as a chain terminator during viral DNA synthesis. However, further research is needed to fully understand its mechanism of action and its potential as an antiviral agent.
Check Digit Verification of cas no
The CAS Registry Mumber 142102-79-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,1,0 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 142102-79:
(8*1)+(7*4)+(6*2)+(5*1)+(4*0)+(3*2)+(2*7)+(1*9)=82
82 % 10 = 2
So 142102-79-2 is a valid CAS Registry Number.
142102-79-2Relevant articles and documents
TSAO derivatives: Highly specific inhibitors of human immunodeficiency virus type-1 (HIV-1) replication
Camarasa,Perez-Perez,Velazquez,San-Felix,Alvarez,Ingate,Jimeno,Karlsson,De Clercq,Balzarini
, p. 585 - 594 (2007/10/02)
TSAO derivatives represent a unique class of nucleosides that are specifically targeted at HIV-1 RT. This overview is focussed on the chemical synthesis, the conformational studies, the antiviral and metabolic properties of TSAO derivatives, as well as th