14257-49-9Relevant articles and documents
Direct synthesis of N-substituted, functionalized aspartic acids using alkali maleates and amines
Piispanen, Peter S.,Pihko, Petri M.
, p. 2751 - 2755 (2007/10/03)
A practical and general one-pot synthesis of mono-N-substituted, functionalized aspartic acids has been developed. The N-substituted aspartic acids are formed directly from alkali maleates and primary amines in hot DMSO. Products from several different primary amines can be prepared chemoselectively in moderate to good yields.