14286-03-4Relevant articles and documents
King, H. J. S.
, (1938)
A novel platinum-based liposome preparation, and its preparation method
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Paragraph 0061; 0062, (2017/02/24)
The invention relates to a novel platinum compound, a liposome preparation containing the compound, a preparation method of the liposome preparation and an application of the liposome preparation in tumor treatment. The main components of the platinum liposome provided by the invention include active platinum compounds, phospholipid, cholesterol, fatty acid and the like, the platinum liposome can be prepared into a freeze-dried powder injection by freeze drying, and the platinum liposome is small in particle size, high in medicine loading capacity and good in stability. The platinum liposome can improve the bioavailability of cisplatin liposome, prolong the residence time of the medicine in vivo and concentrate the cisplatin in cancerous organs, thereby not only reducing the medicine dosage and reinforcing the curative effect, but also capable of reducing the toxic side effects of the medicine, so that the platinum liposome is suitable for treating a variety of tumor diseases.
CARRIER THAT TARGETS FUCOSYLATED MOLECULE-PRODUCING CELLS
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Paragraph 0139, (2015/02/18)
The present invention relates to a carrier that is targeted at fucosylated molecule-producing cells, which comprises an effective amount of fucose for targeting said cells, to a composition comprising the carrier, and to a method for treating and diagnosing a disease related to fucosylated molecule-producing cells utilizing said carrier, etc. The carrier of the present invention enables to deliver a substance specifically to fucosylated molecule-producing cells.
