145986-08-9

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• Basic information

  1. Product Name: Aids004769
  2. Synonyms: .alpha.-L-(+)-(2R,5R)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]uracil;.alpha.-L-Oxathiolanyl uridine;2,4(1H,3H)-Pyrimidinedione, 1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-trans)-;2-Ohme-1,3-oxathiolanu;Aids004769;Aids-004769
  3. CAS NO:145986-08-9
  4. Molecular Formula: C8H10N2O4S
  5. Molecular Weight: 230.241
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 145986-08-9.mol
  9. Article Data: 6

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: 1.521g/cm³
  6. Refractive Index: 1.619
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: Aids004769(CAS DataBase Reference)
  10. NIST Chemistry Reference: Aids004769(145986-08-9)
  11. EPA Substance Registry System: Aids004769(145986-08-9)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 145986-08-9(Hazardous Substances Data)

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• (2R-TRANS)-1-(2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL)URACILCAS

  Cas No: 145986-08-9

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145986-08-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 145986-08-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,9,8 and 6 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 145986-08:
(8*1)+(7*4)+(6*5)+(5*9)+(4*8)+(3*6)+(2*0)+(1*8)=169
169 % 10 = 9
So 145986-08-9 is a valid CAS Registry Number.

InChI:InChI=1/C8H10N2O4S/c11-3-7-14-6(4-15-7)10-2-1-5(12)9-8(10)13/h1-2,6-7,11H,3-4H2,(H,9,12,13)/t6-,7-/m1/s1

145986-08-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione

1.2 Other means of identification

Product number	-
Other names	2-OHMe-1,3-OxathiolanU

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:145986-08-9 SDS

145986-08-9Upstream product

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145986-08-9Relevant articles and documents

TARGETED PROTEIN DEGRADATION

-

Page/Page column 373, (2020/07/14)

This invention provides pharmaceutical protein degraders and E3 ubiquitin ligase binders for therapeutic applications as described further herein.

2-Substituted-4-substituted-1,3-dioxolanes and use thereof

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Page column 45, (2010/11/29)

Nucleoside analogues containing a 1,3-dioxolane structure are suitable antiviral agents, particulary for the treatment of the HIV infections in mammals, especially humans. Examples of the nucleoside analogues include: cis-2-acetoxymethyl-4-(thymin-1′-yl)-1,3,-dioxolane, cis-2-hydroxymethyl-4-(thymin-1′-yl)-1,3-dioxolane, cis-2-benzoyloxymethyl-4-(cytosin-1′-yl)-1,3-dioxolane, and cis-2-hydroxymethyl-4-(cytosin-1′-yl)-1,3-dioxolane. These compounds can be in the form of their racemates or their separate enantiomers.

Processes for preparing substituted 1,3-oxathiolanes with antiviral properties

-

, (2008/06/13)

Disclosed are processes for preparing compounds of the formula (I) and pharmaceutically acceptable salts or esters thereof: STR1 wherein R2 is a purine or pyrimidine base or an analogue or derivative thereof; and Z is S, S=O or SO2.

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