146144-65-2 Usage
General Description
2-Azabicyclo[2.2.2]octane-3-carboxylic acid, also known by its (R)-(9CI) designation, is a chemical compound with a bicyclic structure containing a nitrogen atom. It is a carboxylic acid and is used in the development of pharmaceuticals, particularly as a building block for the synthesis of various drugs. The (R)-(9CI) designation specifies the stereochemistry of the compound, indicating the arrangement of atoms around the chiral center. 2-Azabicyclo[2.2.2]octane-3-carboxylicacid,(R)-(9CI) is an important intermediate in organic synthesis and plays a crucial role in the production of various pharmaceutical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 146144-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,1,4 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 146144-65:
(8*1)+(7*4)+(6*6)+(5*1)+(4*4)+(3*4)+(2*6)+(1*5)=122
122 % 10 = 2
So 146144-65-2 is a valid CAS Registry Number.
146144-65-2Relevant articles and documents
Synthesis and Conformational Studies of Zabicipril (S9650-3), a Potent Inhibitor of Angiotensin Converting Enzyme
Vincent, Michel,Pascard, Claudine,Cesario, Michele,Remond, Georges,Bouchet, Jean-Paul,et al.
, p. 7369 - 7372 (2007/10/02)
The synthesis of the title compound 8c is described.This inhibitor of Angiotensin Converting Enzyme (ACE) contains aza-2 bicyclooctane-carboxylic acid, a bulky cyclic amino acid replacing the proline moiety present in most ACE inhibitors described
