146177-58-4 Usage
Structure
Heterocyclic aromatic compound containing imidazole and quinoxaline rings
Pharmaceutical Relevance
Investigated for anticancer and antifungal properties
Enzyme Inhibition
Studied for inhibiting 3C protease, essential for certain virus replication
Fluorescent Probe
Potential for DNA and RNA detection
Applications
Biomedical and pharmaceutical potential
Check Digit Verification of cas no
The CAS Registry Mumber 146177-58-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,1,7 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 146177-58:
(8*1)+(7*4)+(6*6)+(5*1)+(4*7)+(3*7)+(2*5)+(1*8)=144
144 % 10 = 4
So 146177-58-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H15N5/c1-6-5-9-11(17-13(14)18(9)4)12-10(6)15-7(2)8(3)16-12/h5H,1-4H3,(H2,14,17)
146177-58-4Relevant articles and documents
Synthesis of Mutagenic Methyl- and Phenyl-substituted 2-Amino-3H-imidazoquinoxalines via 2,1,3-Benzoselenadiazoles
Grivas, Spiros,Tian, Wei,Ronne, Erik,Lindstroem, Stefan,Olsson, Kjell
, p. 521 - 528 (2007/10/02)
2-Amino-3-methyl-3H-imidazoquinoxaline, all its derivatives with 1-4 methyl groups in positions 4, 5, 7 and 8, and 2-amino-3,5-dimethyl-7,8-diphenyl-3H-imidazoquinoxaline have been synthesized from the corresponding 6-methylamino-5-nitroquinoxalines through reduction and cyclization with cyanogen bromide.The quinoxalines were obtained from the appropriate α-dicarbonyl compounds and 4-methylamino-3-nitro-1,2-benzenediamines.The latter were prepared from 4-halo-1,2-benzenediamines via 2,1,3-benzoselenadiazoles.The 7- and 8-phenyl derivatives of 2-amino-3,5-dimethyl-3H-imidazoquinoxaline have been synthesized in a slightly different way.
