14624-97-6

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• Basic information

  1. Product Name: 1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE
  2. Synonyms: TIMTEC-BB SBB011765;1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE;1-BENZYL-2-METHYL-1H-1,3-BENZIMIDAZOL-5-AMINE
  3. CAS NO:14624-97-6
  4. Molecular Formula: C₁₅H₁₅N₃
  5. Molecular Weight: 237.3
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 14624-97-6.mol
  9. Article Data: 3

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: 1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE(CAS DataBase Reference)
  10. NIST Chemistry Reference: 1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE(14624-97-6)
  11. EPA Substance Registry System: 1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE(14624-97-6)

• Safety Data

  1. Hazard Codes: Xi
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: IRRITANT
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 14624-97-6(Hazardous Substances Data)

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• 1H-Benzimidazol-5-amine, 2-methyl-1-(phenylmethyl)-

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• Hangzhou J&H Chemical Co., Ltd.
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• 1-Benzyl-2-methyl-1H-1,3-benzimidazol-5-amine

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• 1H-Benzimidazol-5-amine, 2-methyl-1-(phenylmethyl)- CAS No 14624-97-6

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• Hunan Russell Chemicals Technology Co.,Ltd
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• 1-Benzyl-2-methyl-1H-1,3-benzimidazol-5-amine 14624-97-6

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• Shenzhen Foris Technology Co. LTD
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• 1-Benzyl-2-methyl-1H-1,3-benzimidazol-5-amine

  Cas No: 14624-97-6

• USD $ 500.0-500.0 / Gram

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• Pure Chemistry Scientific Inc.
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• 1-benzyl-2-methylbenzimidazol-5-amine

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14624-97-6 Usage

General Description

1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE is a chemical compound with the molecular formula C17H16N2. It is a benzimidazole derivative with a benzyl group and a methyl group attached to the benzimidazole ring. 1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE has been studied for its potential pharmacological properties, including its anti-inflammatory and anticancer activities. It is also used as a building block in the synthesis of various pharmaceuticals and chemical compounds. 1-BENZYL-2-METHYL-1H-BENZOIMIDAZOL-5-YLAMINE has the potential for various applications in the fields of medicine, organic chemistry, and drug discovery.

Check Digit Verification of cas no

The CAS Registry Mumber 14624-97-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,6,2 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14624-97:
(7*1)+(6*4)+(5*6)+(4*2)+(3*4)+(2*9)+(1*7)=106
106 % 10 = 6
So 14624-97-6 is a valid CAS Registry Number.

14624-97-6Upstream product

• 95-54-5 1,2-diamino-benzene 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 1792-40-1 2-methyl-5-nitrobenzimidazole 
• 100-44-7 benzyl chloride 
• 14624-88-5 1-Benzyl-2-methyl-5-nitro-1H-benzimidazole 

14624-97-6Downstream Products

• 73857-59-7 1-benzyl-2-methyl-5-hydrazinobenzimidazole 
• 111055-40-4 1-Benzyl-5-hydroxy-2-methyl-1H-benzimidazole 

14624-97-6Relevant articles and documents

Triazine-benzimidazole hybrids: Anticancer activity, DNA interaction and dihydrofolate reductase inhibitors

Singla, Prinka,Luxami, Vijay,Paul, Kamaldeep

, p. 1691 - 1700 (2015/03/30)

A new series of triazine-benzimidazole hybrids has been synthesized with different substitution of primary and secondary amines at one of the position of triazine in moderate to good yields. These compounds were evaluated for their inhibitory activities over 60 human tumor cell lines at one dose and five dose concentrations. Compounds 6b, 8 and 9 showed broad spectrum of antitumor activities with GI50 values of 9.79, 2.58 and 3.81 μM, respectively. DNA binding studies also indicated strong interaction properties of these compounds. These synthesized compounds also showed inhibition of mammalian dihydrofolate reductase (DHFR). Compound 6b was depicted as the most active member of DHFR inhibitor with IC50 value of 1.05 μM. Molecular modelling studies were used to identify the stabilized interactions of Compound 6b within the active site of enzyme for DHFR.

Synthesis and antimycotic activity of some benzyloxymino compounds

Garuti,Giovanninetti,Ferranti,Chiarini,Bertocchi,Sabatino,Brigidi

, p. 378 - 381 (2007/10/02)

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